SFI 2016

28 to 30 November 2016 - Cité des Sciences et de l’Industrie, Paris, France

SFI 2016 header

Monday 28 November

08:00-08:30

Espaces S1/S2Welcome coffee

08:30-09:00

Welcome Introduction

Amphi. Gaston Berger

Hans Yssel - SFI President
Anne Hosmalin - SFI Past-President
Alain Fischer - Congress President
Yves Lévy - CEO Inserm  Logo Inserm
Catherine Jessus, Bruno Lucas - CNRS INSB Director and DAS  Logo CNRS

09:00-10:30

Plenary Session: François Kourilsky lecture  Logo Universite-Paris-Descartes

Amphi. Gaston Berger

Chairs: Michel Fougereau - Centre d’Immunologie de Marseille-Luminy, Université Aix-Marseille, Inserm, CNRS - Marseille (FR) and Jean-Claude Weill - Institut Necker Enfants Malades, Inserm, CNRS, Université Paris V-USPC - Paris (FR)

  • Max Cooper - Emory University - Atlanta (US): Evolution of lymphocyte-based immunity
10:30-11:15

Espaces S1/S2Coffee break - Visit of exhibition - Poster session

Parallel Sessions

11:15-12:45

German Society for Immunology (DGfI): Biology of B cells  Logo DGfI

Salle Louis Armand Ouest

Chair: Marta Rizzi - Universitäts Klinikum Freiburg - Freiburg (DE)

  • Andreas Radbruch - German Rheumatology Research Center - Berlin (DE): Memory plasma cells and memory B cells
  • Klaus Rajewsky - Max Delbrück Center for Molecular Medicine - Berlin (DE): A mouse model of Epstein-Barr-Virus infection
  • Kathrin Pieper - Institute for Research in Biomedicine - Bellinzona (CH): A new mechanism of immunoglobulin diversification generates broadly reactive antibodies to Plasmodium falciparum
  • Jürgen Wienands - Georg August University of Göttingen (DE): Primary and secondary B cell activation

11:15-12:45

Checkpoint inhibitors against cancer

Amphi. Gaston Berger

Chairs: Antoine Toubert - Institut Universitaire d'Hématologie, Inserm, Université Paris VII-USPC - Paris (FR) and Eric Tartour - Paris Cardiovascular Research Center, Université Paris V-USPC - Paris (FR)

  • Laurence Zitvogel - Institut Gustave-Roussy, Inserm, Université Paris XI - Villejuif (FR): Oncobiotics ameliorate immune checkpoint blockade
  • Caroline Robert - Institut Gustave-Roussy, Inserm, Université Paris XI - Villejuif (FR): Melanoma, a model for immunotherapy

Selected short oral presentations

  • Magalie Dosset - Inserm, EFS, UBFC - Besançon (FR): Immunogenic cell death inducers trigger PD-L1-dependent adaptive immune resistance to cancer
  • Laurie Menger - Institut Curie, Inserm - Paris (FR): TALEN-Mediated Inactivation of PD-1 in tumor-reactive lymphocytes promotes intratumoral T-cell persistence and rejection of established tumors
  • Sylvain Simon - Inserm - Nantes (FR): Emergence of high avidity Melan-A specific neoclonotypes defined by high PD-1 and TIGIT co-expression in melanoma patients responding to anti-PD1 treatment

11:15-12:45

ILC, NKT and MAIT cells

Salle Louis Armand Est

Chairs: Anne Caignard - Institut Universitaire d'Hématologie, Inserm, Université Paris Diderot-USPC - Paris (FR) and Maria Leite-de-Moraes - Institut Necker-Enfants Malades Inserm, CNRS, Université Paris V-USPC - Paris (FR)

  • James Di Santo - Institut Pasteur, Inserm - Paris (FR): Transcriptional regulation of innate lymphoid cell differentiation
  • Agnès Lehuen - Institut Cochin, Inserm, CNRS, Université Paris V-USPC - Paris (FR): MAIT cells at the crossroad of microbiota, inflammation and diabetes

Selected short oral presentations

  • Christelle Harly - National Institute of Health - Bethesda (US): TCF7 coordinates a transcriptional program underlying early innate lymphoid cell development that overlaps with the T cell developmental program
  • Nicolas Huot - Institut Pasteur - Paris (FR): Migration of NK cells into B cell follicles during SIVagm infection
  • Marie-Laure Michel - Institut Necker-Enfants Malades - Paris (FR): SLAM-associated protein favors the development of iNKT2 over iNKT17 cells
12:45-14:45

Espaces S1/S2Lunch - Coffee - Visit of exhibition - Poster session

13:45-14:45
ASSIM General Assembly

Salle Louis Armand Ouest

13:45-14:45

LabEx Milieu Intérieur  Logo Milieu Intérieur

Salle Louis Armand Est

Chair: Matthew Albert - Institut Pasteur, Inserm - Paris (FR) / Genentech - San Francisco (US)

  • Darragh Duffy - Institut Pasteur, Paris (FR): Defining the boundaries of a healthy immune response for a better understanding of disease
  • Jacques Fellay - École Polytechnique Féderale de Lausanne (CH): Human genetics of immune responses
  • Stanislas Mondot - INRA, Paris (FR): Exploring the human gut microbiota composition in relation to immune system variance: what has to be revealed?
14:45-16:15

Plenary Session: Basis of cancer immunotherapy

Amphi. Gaston Berger

Chairs: Anne Durandy - Institut Imagine, Inserm, Université Paris V-USPC - Paris (FR) and Hervé Fridman - Centre de Recherche des Cordeliers, Inserm, Université Paris V-USPC - Paris (FR)

  • Tasuku Honjo - Kyoto University (JP): Cancer immunotherapy by PD-1 blockade
  • Michel Sadelain - Memorial Sloan Kettering Institute - New York (US): CAR therapy beyond the CD19 paradigm
16:15-17:00

Espaces S1/S2Coffee break - Visit of exhibition - Poster session

Parallel Sessions

17:00-18:30

Acteria Alumni Session   Logo Acteria

Salle Louis Armand Ouest

Chairs: Anne Hosmalin - Institut Cochin, Inserm, CNRS, Université Paris V-USPC - Paris (FR) and Hans Yssel - Centre d'Immunologie et des Maladies Infectieuses, Inserm, Université Paris VI, Sorbonne Universités - Paris (FR)

  • Nicolas Manel - Institut Curie, Inserm - Paris (FR): Interactions of Dendritic Cells with Viruses
  • Dietmar Zehn - Technical University of Munich - Freising (DE): T Cell subset diversification in chronic infections
  • Chris Schiering - Francis Crick Institute - London (UK): Feedback control of AhR signalling regulates intestinal immunity
  • Thomas Marichal - GIGA-Research Institute - Liège (BE): Role of keratinocyte RAB guanine nucleotide exchange factor 1 (RABGEF1) in skin homeostasis
  • Alexander Eggel - Institute of Immunology, University of Bern (CH): Therapeutic approaches to interfere with IgE-mediated allergic reactions

17:00-18:30

Anti-tumor immunity   Logo labex IGO

Amphi. Gaston Berger

Chairs: Nathalie Labarrière - Université de Nantes, Inserm, CNRS - Nantes (FR) and Jean-Luc Teillaud - Centre de Recherche des Cordeliers, Inserm, Université Paris V-USPC - Paris (FR)

  • Nathalie Bendriss-Vermare - Centre de Recherche en Cancérologie de Lyon, Inserm, CNRS, Université de Lyon (FR): Dual role of plasmacytoid dendritic cells in breast cancer immunity and therapeutic functional reprogramming
  • Jérôme Galon - Centre de Recherche des Cordeliers, Inserm, Université Paris V-USPC - Paris (FR): From immune contexture to Immunoscore in the era of cancer immunotherapies
  • Éric Vivier - Centre d’Immunologie de Marseille-Luminy, Université Aix-Marseille, Inserm, CNRS - Marseille (FR): Evidence of innate lymphoid cell redundancy in mice and humans

17:00-18:30

B cells

Salle Louis Armand Est

Chairs: Claudine Schiff - Centre d'Immunologie de Marseille-Luminy, Université Aix-Marseille, Inserm, CNRS - Marseille (FR) and François Huetz - Institut Pasteur, Inserm - Paris (FR)

  • Michel Cogné - CNRS, Université et CHU de Limoges (FR): Dragged with an Ig super-enhancer
  • Claude-Agnès Reynaud - Institut Necker Enfants Malades, Inserm, CNRS, Université Paris V-USPC - Paris (FR): A large IgM memory subset in mouse spleen is constantly renewed by persistent clones from Peyer's patches immune responses

Selected short oral presentations

  • Nagham Alouche - Inserm - Clamart (FR): CXCR4 desensitization regulates TLR-mediated plasma cell differentiation and persistence
  • Florent Arbogast - Institut de Biologie Moléculaire et Cellulaire Strasbourg, CNRS - Strasbourg (FR): Macroautophagy in B cells activation and antigen presentation
  • Vincent Gies - Institut de Biologie Moléculaire et Cellulaire Strasbourg, CNRS - Strasbourg (FR): Human thymic B cells have an APC phenotype and express AIRE
18:30-19:00

Plenary Session

Amphi. Gaston Berger

Chair: Hans Yssel

  • Jean-Marc Cavaillon - Institut Pasteur, Inserm - Paris (FR): Centenary of the death of Elie Metchnikoff: a visionary and an outstanding team leader
19:00

Espaces S1/S2Welcome cocktail
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