Thursday 16 January
08:50-09:00
Welcome address
- Béhazine Combadière (Inserm, CIMI Paris, FR)
09:00-09:45
Opening lecture
- History of pertussis vaccine: from basic to clinic
Camille Locht (Institut Pasteur, Lille, FR)
SESSION 1 - Basic vaccinology
Chairs: Anne Hosmalin and Jean-Claude Sirard
09:45-10:15
- Skin immunisation orchestrates protective immune connectivity
Linda Klavinskis (King's College London, UK)
10:15-10:45
- Better Epitope Discovery, Precision Immune Engineering and Accelerated Vaccine Design by Immunoinformatics
Anne De Groot (EpiVax, USA)
10:45-11:00
Coffee break and Posters
11:00-11:30
- Induction of neutralizing HIV antibodies by native-like SOSIP trimers
Rogier Sanders (AMC, Netherlands)
11:30-12:00
- Overview on a nanoparticulate vaccine against Toxoplasma gondii infection
Didier Betbeder (Vaxinano, Lille, FR)
12:00-13:30
Selected short oral presentations
- Gp41 W614A-3S peptide-conjugated vaccine formulated in squalene emulsion promotes broadly neutralizing antibodies against HIV-1
Chloé Chaudesaigues (Inserm, Paris, FR) - The GM-CSF released by airway epithelial cells orchestrates the mucosal adjuvant activity of flagellin
Jean-Claude Sirard (Institut Pasteur, Lille, FR) - Induction of tumor-specific CD8+ T cell responses through nanoparticle-mediated delivery of tumor self Ag and alpha-GalCer to cross priming dendritic cells
François Trottein (Institut Pasteur, Lille, FR) - MOPEVAC, a pan-arenavirus vaccine platform that protects cynomolgus monkeys against Lassa and Machupo viruses after a single shot
Sylvain Baize (Institut Pasteur, Lyon, FR) - Cross-protection efficacy of a recombinant vaccine against Lassa fever
Mathieu Mateo (Institut Pasteur, Lyon, FR)
13:30-14:30
Lunch and Posters
SESSION 2 - Systems vaccinology
Chairs: Claude Leclerc and Nathalie Garçon
14:30-15:00
- Microbiota and rotavirus vaccination
Vanessa Harris (AIGHD, Netherlands)
15:00-15:30
- Application of adjuvant for vaccine and immunotherapy; machine learning versus classical immunology
Ken Ishii (University of Tokyo, Japan)
15:30-16:00
- Learnings from translational research in understanding the role of adjuvants in vaccine
Arnaud Didierlaurent (GSK, Belgium)
16:00-16:15
Coffee break and Posters
16:15-16:45
- Dissecting immune responses in veterinary species using systems immunology approaches
Artur Summerfield (University of Bern, Switzerland)
16:45-18:15
Selected short oral presentations
- OVX836, A novel universal influenza A vaccine candidate: short-term results of a phase I clinical trial in humans
Florence Nicolas (Osivax, Lyon, FR) - Analyzing cellular immunogenicity in vaccine trials: a new statistical method including non-specific responses for accurate estimation of vaccine effects
Edouard Lhomme (Inserm U1219 Bordeaux Population Health, Bordeaux, FR) - Identification of biomarkers by Machine Learning from cytometry data
Julien Nourikyan (AltraBio SAS, Lyon, FR) - A CyaA recombinant vaccine induces a specific Th-1 immune response and protects dogs against severe Bordetella bronchiseptica infection
Severine Boullier (National veterinary school of Toulouse, Toulouse, FR) - Swine influenza A virus infection inhibits PRRS MLV replication in piglets but does not interfere with vaccine protection
Patricia Renson (Anses, Ploufragan, FR)
18:15