SFI-SPI 2026

PARALLEL SESSIONS

PS11 - Innate T cells

Chairs: Maria LEITE DE MORAES (Paris, France) & Christophe PAGET (Tours, France)

• Graham OGG (University of Oxford, Oxford, United Kingdom)
  CD1a-reactive T cells and lipid antigens in inflammatory skin diseases: discovery and translation
• Agnès LEHUEN (Institut Cochin, INSERM U1016, UMR 8104, Paris, France)
  MAIT cells and microbiota interaction in autoimmunity and viral infection

+ Selected short oral presentations

• PS11-01 - Youenn JOUAN (INSERM U1100, Université de Tours, Tours, Indre et Loire, France)
  MAIT cells promote lung resilience during severe viral pneumonia by maintaining myeloid balance
• PS11-02 - Camille KERGARAVAT (Saint Louis Research Institute, Paris, France)
  Developmental waves and genetic regulation of the Human γδ T-cell repertoire
• PS11-03 - Juan SIENES BAILO (Immunoregulation Unit, Department of Immunology, Institut Pasteur, Université Paris Cité, Paris, France)
  IL-23 regulates the non-canonical NF-kB pathway in human invariant Natural Killer T (iNKT) cells

PS12 - Women’s health/sex bias in immunity

Chairs: Ricardo SILVESTRE (Braga, Portugal) & Anne ASTIER (Toulouse, France)

• Nils LANDEGREN (Uppsala University, Sweden)
• Sophie LAFFONT-PRADINES (Infinity -Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, Inserm, CNRS, Toulouse, France)
  Hormonal regulation of ILC : consequences on lung immunity

+ Selected short oral presentations

• PS12-01 - Léa FERRAYÉ (Toulouse Institute for Infectious and Inflammatory Diseases, Toulouse, France)
  Tlr7 bi-allelism shapes pathogenic female B cell responses in lupus
• PS12-02 - Aymeline DEBONLIER (INFINITy, Toulouse, France)
  PI3K/AKT signaling controls sex bias in Tr1 cells and their response to vitamin D
• PS12-03 - Hélène VANTOMME (i3 laboratory, Sorbonne University, Paris, France)
  Sex-associated differences in human thymic TCR selection

PS13 - T and B cell memory

Chairs: Marion ESPELI (Paris, France) & Klaas VAN GISBERGEN (Lisbon, Portugal)

• Klaas VAN GISBERGEN (Champalimaud Foundation, Lisbon, Portugal)
  T cell diversification in response to infection and tumor development
• Christina ZIELINSKI (University of Cambridge, United Kingdom)

+ Selected short oral presentations

• PS13-01 - Maria KERIDON (Physiology and Cancer Department, Champalimaud Foundation, Lisbon, Portugal)
  Clearance of tumor antigen governs the differentiation of bona fide CD8+ tissue-resident memory T cells
• PS13-02 - Marc VOCANSON (Team EIA, Centre International de Recherche en Infectiologie, Lyon, France)
  Progressive remodeling of pathogenic skin resident memory T cell subsets shapes long-term allergic memory
• PS13-03 - Andrea PICHLER (INFINITY, Toulouse, Midi-Pyrénées, France)
  PI3Kd promotes T cell effector differentiation during chronic infection

CPS14 - CAR-T cells in autoimmune diseases

Clinical session

Chairs: Roland LIBLAU (Toulouse, France) & Jean-Daniel LELIEVRE (Créteil, France)

• Maxime TEISSEYRE (Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France)
  CAR-T cell therapy for refractory autoimmune diseases
• Maurine JOURET (Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon, France)
  CAR-T cell therapy for juvenile-onset autoimmune diseases: a promising future?

Foyer & Concorde 1&2 - Level -1Coffee break - Visit of exhibition & Posters

PLENARY SESSIONS

Audit. Saint-Exupéry - Level 2SESSION 2 - Host-pathogen interactions

Chairs: Ricardo SILVESTRE (Braga, Portugal) & Emmanuelle JOUANGUY (Paris, France)

• Judi ALLEN (Wellcome Centre for Cell-Matrix Research, Lydia Becker Institute for Immunology & Infection, University of Manchester, Manchester, United Kingdom)
• Etienne MEUNIER (Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France)
  The NLRP1 inflammasome: Scanning the borders

+ Selected short oral presentations

• P2-01 - Vasco RODRIGUES (INSERM U932, Institut Curie, Paris, Île-de-France, France)
  Constitutive macropinocytosis is coupled with reduced rates of protein synthesis to confer intrinsic protection against viral replication in macrophages
• P2-02 - Léa FROMONT (IPBS, TOULOUSE, France)
  LiveLung-TB: Intravital imaging reveals CD4⁺ T-cell dynamics during pulmonary Mycobacterium tuberculosis infection
• P2-03 - Rute Daniela MATOS GONÇALVES (i3s - Instituto de Investigação e Inovação em Saúde, Porto, Portugal)
  Mycobacterium tuberculosis isolates modulate levels of protective IL-1β in vivo accounting for disease severity

Audit. Saint-Exupéry - Level 2Industry Symposia

Chairs: Nicolas FAZILLEAU (Toulouse, France) & Emmanuelle JOUANGUY (Paris, France)

Foyer & Concorde 1&2 - Level -1Lunch - Coffee - Visit of exhibition & Posters

PARALLEL SESSIONS

PS15 - Neutrophils

Chairs: Véronique WITKO (Paris, France) & Patrice DECKER (Paris, France)

• Triantafyllos CHAVAKIS (Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine, Dresden, Germany)
  Trained granulopoiesis in cancer
• Audrey BERNUT (Laboratory of Pathogens and Host Immunity, Université de Montpellier, CNRS, INSERM, Montpellier, France)
  Making waves: rebalancing neutrophil responses in cystic fibrosis
  From inflammation to resolution using zebrafish

+ Selected short oral presentations

• PS15-01 - Camille DANNE (UMRS938, Paris, France)
  The microbiota-derived metabolite Metab1 prevents neutrophil activation by inducing metabolic quiescence
• PS15-02 - Patrice DECKER (University Sorbonne Paris Nord, Bobigny, France)
  NETs from rheumatoid arthritis patients trigger a pro-inflammatory response in monocytes through metabolic mechanisms and modulate macrophage differentiation
• PS15-03 - Aya CHAMAA (T-RAIG, TIMC, La Tronche, France)
  Role of neutrophils in Chlamydia driven Reactive arthritis in the SKG mouse

PS16 - Gene and cell therapy

Chairs: Makoto MIYARA (Paris, France) &
Jacques NUNES (Marseille, France)

• Makoto MIYARA (Immunology Department, INSERM, Centre d'Immunologie et des Maladies Infectieuses (CIMI), AP-HP, Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France)
• Alena GROS (Vall d’Hebron Institute of Oncology (VHIO), Tumor Immunology & Immunotherapy Group, Barcelona, Spain)

+ Selected short oral presentations

• PS16-01 - Sofia MENSURADO (Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal)
  Allogeneic CARγδT-cells recognize CD33 and PVR to target Acute Myeloid Leukemia and suppress tumor progression
• PS16-02 - Janie ROBERT (Sorbonne University - Inserm UMRS959, Paris, France)
  IL-2 self-sufficient CAR-Tregs targeting oxidation-specific epitopes for inflammation-directed immunotherapy
• PS16-03 - Mariana GADELHO GONÇALVES (Immune Cell Reprogramming Lab., Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal)
  A ‘Sense-and-Reprogram’ Platform for Systemic Cancer Immunotherapy

PS17 - Germinal Center

Chairs: Amélie BONAUD (Limoges, France) & Fréderic MOURCIN (Rennes, France)

• Mauro GAYA (Center for Immunology of Marseille-Luminy (CIML), Marseille, France)
  B cell immunity to mucosal antigens
• Reina MEBIUS (Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands)

+ Selected short oral presentations

• PS17-01 - Raphaël JEGER-MADIOT (INSERM U1151/CNRS UMR 8253, Université Paris Cité, Institut Necker Enfants Malades, Paris, France)
  Modeling memory B cell responses in spleen-derived immune organoids
• PS17-02 - Maya POLKOTYCKI (INFINITY U1291 INSERM, Toulouse, France)
  Type 3 inflammation shapes the Follicular Regulatory T cells (Tfr) into a Tfr17 polarized subset
• PS17-03 - Audrey AKESSE (Control of the immune response B and lymphoproliferation, CNRS UMR 7276, INSERM, University of Limoges, Limoges, France)
  Plasma cell heterogeneity is imprinted by the type of immune challenge

CPS18 - Xenotransplantation

Clinical session

Chairs: Alice KOENIG (Lyon, France) & Julien ZUBER (Paris, France)

• Olivier THAUNAT (CIRI, INSERM, Université Claude Bernard Lyon I, CNRS, École Normale Supérieure de Lyon, Université de Lyon, Lyon, France)
  Breaking Barriers Across Species: The Immunopathological Frontiers of Xenotransplantation
• Aurélie SANNIER (Hôpital Bichat - Claude-Bernard, Paris, France)
  Lessons from the First Human Xenotransplants

Foyer & Concorde 1&2 - Level -1 Coffee break - Visit of exhibition & Posters

PARALLEL SESSIONS

PS19 - Mastcells / Basophils

Chairs: Gaël MÉNASCHÉ (Paris, France) & Nicolas CHARLES (Paris, France)

• Sebastien TALBOT (Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden)
  Nociceptor neurons impact anti-tumor immunity
• Clare LLOYD (National Heart and Lung Institute, Imperial College London, London, United Kingdom)

+ Selected short oral presentations

• PS19-01 - Céline EL SAMROUT (Infinity, INSERM, Toulouse, France; 2 IRSD, INSERM, Toulouse, France)
  Non-immune function of myenteric mast cells in supporting neuronal plexus homeostasis
• PS19-02 - Geoffrey CHEMINET (Hematology Laboratory, Imagine Institute for Genetic Diseases - U1163 INSERM, Paris, France)
  Role of mast cells in bone vaso-occlusive crisis and pain of sickle cell disease
• PS19-03 - Zohra BENMESSAOUD (INSERM UMR1291 – CNRS UMR5051 - University Toulouse III, Infinity, Toulouse, France)
  A new mouse model expressing human IgE and its receptors FcεRI and CD23 predicts a superiority for ligelizumab over omalizumab in anaphylaxis

PS20 - Mucosal immunology

Chairs: Klaas VAN GISBERGEN (Lisbon, Portugal) & Olivier NEYROLLES (Toulouse, France)

• Nicole JOLLER (Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland)
  Fungal infections imprint the Th17 pool by establishing a distinct memory Th17 population
• Andreas DIEFENBACH (Laboratory of Innate Immunity, Institute of Microbiology, Infectious Diseases and Immunology (I-MIDI), Berlin, Germany)

+ Selected short oral presentations

• PS20-01 - Margaux PARADIS (IPBS - CNRS, Toulouse, France)
  A TAK1-Driven NLRP1 Inflammasome Pathway Revealed by Phosphatase Targeting Environmental Toxins
• PS20-02 - Fabian GUENDEL (Microenvironment and Immunity Unit, Institut Pasteur, Paris, France)
  The Postnatal Stress Response Drives Long-Term Maladaptation of the Intestinal Epithelium via TLR3/TRIF Epigenetic Memory
• PS20-03 - Ignacio CABALLERO POSADAS (INRAE, Toxalim, Toulouse, France)
  TLR5 signaling amplifies airway epithelial cell responses to type I interferon through MyD88–JAK1 crosstalk during influenza infection in pigs

PS21 - Tissue homeostasis and dynamics

Chairs: Julie RIBOT (Lisbon, Portugal) & Meryem ALOULOU (Toulouse, France)

• Julie RIBOT (Gulbenkian Institute for Molecular Medicine (GIMM), Lisbon, Portugal)
  Stressing the role of γδ17 T cells at the crossroads of tissue communication and pathophysiology
• Karl BALABANIAN (Université Paris Cité, Institut de Recherche Saint-Louis, INSERM, Paris, France)
  CXCR4 signaling, a gatekeeper orchestrating the bone marrow ecosystem

+ Selected short oral presentations

• PS21-01 - Miguel MESQUITA (Gulbenkian Institute for Molecular Medicine (GIMM), Avenida Professor Egas Moniz, Oeiras, Portugal)
  Ferroptosis is a Physiologic Vulnerability of Iron-Recycling Macrophages
• PS21-02 - Dan CORRAL (INFINITY, Toulouse, France)
  Let it flow: Maternal immune regulation of lactation
• PS21-03 - Chloé MICHAUDEL (MTS - LIAA, INRAE, Gif sur Yvette Cedex, France)
  Low-dose perinatal pesticide exposure reprograms immune development in male offspring and increases susceptibility to type-2 airway inflammation

CPS22 - FIM General Assembly

Clinical session

PLENARY SESSION

Audit. Saint-Exupéry - Level 2Young investigators

Chairs: Marie-Astrid BOUTET (Nantes, France), Joaquin PELLEGRINI (Toulouse, France), Mehdi BENAMAR (Montpellier, France), Catarina AZEVEDO (Porto, Portugal) & Inês ALVES (Porto, Portugal)

• Thomas MARICHAL (GIGA Institute, University of Liège, Liège, Belgium)
  A deep dive into the biology of lung myeloid cells in health and disease

+ Selected short oral presentations

• P3-01 - Camille CHATELAIN (Division of Immuno-oncology, Lund Stem Cell Center, Lund University, Lund, Sweden)
  Inducing immunogenic lymphoid structures across cancers by tumor-to-dendritic cell reprogramming
• P3-02 - Ana Carolina VALENTE SANTOS CRUZ DE ARAUJO (Department of Immunology, University of São Paulo, São Paulo, São Paulo, Brazil)
  HIF-1α licenses BCG-induced trained immunity to promote pulmonary and systemic protection against Brucella abortus infection
• P3-03 - Tomás MACHADO (University of Coimbra, Center for Innovative Biomedicine and Biotechnology, Center for Neuroscience and Cell Biology, Cantanhede, Coimbra, Portugal)
  Retinoic acid modulates invariant Natural Killer T cell development and function in colon cancer

Congress Dinner