SFI-SPI 2026

PARALLEL SESSIONS

Ariane 1 - Level 1 PS11 - Innate T cells

Chairs: Maria LEITE DE MORAES (Paris, France) & Julie DÉCHANET-MERVILLE (Bordeaux, France)

• Graham OGG (University of Oxford, Oxford, United Kingdom)
  CD1a-reactive T cells and lipid antigens in inflammatory skin diseases: discovery and translation
• Agnès LEHUEN (Institut Cochin, INSERM U1016, UMR 8104, Paris, France)
  MAIT cells in autoimmune and infectious diseases

+ Selected short oral presentations

• PS11-01 - Youenn JOUAN (INSERM U1100, Université de Tours, Tours, Indre et Loire, France)
  MAIT cells promote lung resilience during severe viral pneumonia by maintaining myeloid balance
• PS11-02 - Camille KERGARAVAT (Saint Louis Research Institute, Paris, France)
  Developmental waves and genetic regulation of the Human γδ T-cell repertoire
• PS11-03 - Juan SIENES BAILO (Immunoregulation Unit, Department of Immunology, Institut Pasteur, Université Paris Cité, Paris, France)
  IL-23 regulates the non-canonical NF-kB pathway in human invariant Natural Killer T (iNKT) cells

Guillaumet 1+2 - Level 2 PS12 - Women’s health/sex bias in immunity

Chairs: Ricardo SILVESTRE (Braga, Portugal) & Anne ASTIER (Toulouse, France)

• Nils LANDEGREN (Uppsala University, Sweden)
• Sophie LAFFONT-PRADINES (Infinity -Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, Inserm, CNRS, Toulouse, France)
  Hormonal regulation of ILC: consequences on lung immunity

+ Selected short oral presentations

• PS12-01 - Léa FERRAYÉ (Toulouse Institute for Infectious and Inflammatory Diseases, Toulouse, France)
  Tlr7 bi-allelism shapes pathogenic female B cell responses in lupus
• PS12-02 - Aymeline DEBONLIER (INFINITy, Toulouse, France)
  PI3K/AKT signaling controls sex bias in Tr1 cells and their response to vitamin D
• PS12-03 - Hélène VANTOMME (i3 laboratory, Sorbonne University, Paris, France)
  Sex-associated differences in human thymic TCR selection

Audit. Saint-Exupéry - Level 2PS13 - T and B cell memory

Chairs: Marion ESPELI (Paris, France) & Klaas VAN GISBERGEN (Lisbon, Portugal)

• Klaas VAN GISBERGEN (Champalimaud Foundation, Lisbon, Portugal)
  T cell diversification in infection and cancer
• Christina ZIELINSKI (University of Cambridge, United Kingdom)
  Regulation of human T cell cytotoxicity - a novel modality to kill

+ Selected short oral presentations

• PS13-01 - Maria KERIDON (Physiology and Cancer Department, Champalimaud Foundation, Lisbon, Portugal)
  Clearance of tumor antigen governs the differentiation of bona fide CD8+ tissue-resident memory T cells
• PS13-02 - Marc VOCANSON (Team EIA, Centre International de Recherche en Infectiologie, Lyon, France)
  Progressive remodeling of pathogenic skin resident memory T cell subsets shapes long-term allergic memory
• PS13-03 - Andrea PICHLER (INFINITY, Toulouse, Midi-Pyrénées, France)
  PI3Kd promotes T cell effector differentiation during chronic infection

Cassiopée - Level 1CPS14 - CAR-T cells in autoimmune diseases

Clinical session

Chairs: Roland LIBLAU (Toulouse, France) & Jean-Daniel LELIEVRE (Créteil, France)

• Maxime TEISSEYRE (Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France)
  CAR-T cell therapy for refractory autoimmune diseases
• Maurine JOURET (Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospices Civils de Lyon, Lyon, France)
  CAR-T cell therapy for juvenile-onset autoimmune diseases: a promising future?

Foyer & Concorde 1&2 - Level -1Coffee break - Visit of exhibition & Posters

PLENARY SESSIONS

Audit. Saint-Exupéry - Level 2SESSION 2 - Host-pathogen interactions

Chairs: Ricardo SILVESTRE (Braga, Portugal) & Emmanuelle JOUANGUY (Paris, France)

• Judi ALLEN (Wellcome Centre for Cell-Matrix Research, Lydia Becker Institute for Immunology & Infection, University of Manchester, Manchester, United Kingdom)
• Etienne MEUNIER (Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France)
  The NLRP1 inflammasome: Scanning the borders

+ Selected short oral presentations

• P2-01 - Vasco RODRIGUES (INSERM U932, Institut Curie, Paris, Île-de-France, France)
  Constitutive macropinocytosis is coupled with reduced rates of protein synthesis to confer intrinsic protection against viral replication in macrophages
• P2-02 - Léa FROMONT (IPBS, Toulouse, France)
  LiveLung-TB: Intravital imaging reveals CD4⁺ T-cell dynamics during pulmonary Mycobacterium tuberculosis infection
• P2-03 - Rute Daniela MATOS GONÇALVES (i3s - Instituto de Investigação e Inovação em Saúde, Porto, Portugal)
  Mycobacterium tuberculosis isolates modulate levels of protective IL-1β in vivo accounting for disease severity

Audit. Saint-Exupéry - Level 2Industry Symposium

Chairs: Nicolas FAZILLEAU (Toulouse, France) & Emmanuelle JOUANGUY (Paris, France)

• Sony
  Clone War: Performance and Interoperability of Two ID7000 Spectral Flow Cytometers
  Hugo GARNIER (Ingénieur d’Études, Plateau Technique de Cytométrie et Tri Cellulaire, Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Toulouse, France)

Audit. Saint-Exupéry - Level 2Industry Talks

Chairs: Nicolas FAZILLEAU (Toulouse, France) & Emmanuelle JOUANGUY (Paris, France)

• CeGaT
  Title upcoming
  Lara EL BAZZAL (CeGaT, Tuebingen, Germany)

• Agilent Technologies

Foyer & Concorde 1&2 - Level -1Lunch - Coffee - Visit of exhibition & Posters

PARALLEL SESSIONS

Guillaumet 1+2 - Level 2PS15 - Neutrophils

Chairs: Véronique WITKO (Paris, France) & Patrice DECKER (Paris, France)

• Triantafyllos CHAVAKIS (Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine, Dresden, Germany)
  Trained granulopoiesis in cancer
• Audrey BERNUT (Laboratory of Pathogens and Host Immunity, Université de Montpellier, CNRS, INSERM, Montpellier, France)
  Making waves: rebalancing neutrophil responses in cystic fibrosis
  From inflammation to resolution using zebrafish

+ Selected short oral presentations

• PS15-01 - Camille DANNE (UMRS938, Paris, France)
  The microbiota-derived metabolite Metab1 prevents neutrophil activation by inducing metabolic quiescence
• PS15-02 - Patrice DECKER (University Sorbonne Paris Nord, Bobigny, France)
  NETs from rheumatoid arthritis patients trigger a pro-inflammatory response in monocytes through metabolic mechanisms and modulate macrophage differentiation
• PS15-03 - Aya CHAMAA (T-RAIG, TIMC, La Tronche, France)
  Role of neutrophils in Chlamydia driven Reactive arthritis in the SKG mouse

Audit. Saint-Exupéry - Level 2PS16 - Gene and cell therapy

Chairs: Makoto MIYARA (Paris, France) &
Jacques NUNES (Marseille, France)

• Makoto MIYARA (Immunology Department, INSERM, Centre d'Immunologie et des Maladies Infectieuses (CIMI), AP-HP, Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France)
  Human Treg cell therapies for transplantation
• Alena GROS (Vall d’Hebron Institute of Oncology (VHIO), Tumor Immunology & Immunotherapy Group, Barcelona, Spain)
  Personalized T-cell therapies for solid cancers

+ Selected short oral presentations

• PS16-01 - Sofia MENSURADO (Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal)
  Allogeneic CARγδT-cells recognize CD33 and PVR to target Acute Myeloid Leukemia and suppress tumor progression
• PS16-02 - Mariana GADELHO GONÇALVES (Immune Cell Reprogramming Lab., Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal)
  A ‘Sense-and-Reprogram’ Platform for Systemic Cancer Immunotherapy
• PS16-03 - Annemarie FORTUIN (Team 3 - Institute for Regenerative Medicine and Biotherapy, Montpellier, France)
  Engineering Regulatory T Cells For Rheumatoid Arthritis: Development and Evaluation of CAR Constructs

Cassiopée - Level 1PS17 - Germinal Center

Chairs: Amélie BONAUD (Limoges, France) & Fréderic MOURCIN (Rennes, France)

• Mauro GAYA (Center for Immunology of Marseille-Luminy (CIML), Marseille, France)
  The lung stroma sustains a plasma cell niche for long-term mucosal protection against infection
• Reina MEBIUS (Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands)
  The immune regulating microenvironment of lymph nodes

+ Selected short oral presentations

• PS17-01 - Raphaël JEGER-MADIOT (INSERM U1151/CNRS UMR 8253, Université Paris Cité, Institut Necker Enfants Malades, Paris, France)
  Modeling memory B cell responses in spleen-derived immune organoids
• PS17-02 - Maya POLKOTYCKI (INFINITY U1291 INSERM, Toulouse, France)
  Type 3 inflammation shapes the Follicular Regulatory T cells (Tfr) into a Tfr17 polarized subset
• PS17-03 - Audrey AKESSE (Control of the immune response B and lymphoproliferation, CNRS UMR 7276, INSERM, University of Limoges, Limoges, France)
  Plasma cell heterogeneity is imprinted by the type of immune challenge

Ariane 1 - Level 1 CPS18 - Xenotransplantation

Clinical session

Chairs: Alice KOENIG (Lyon, France) & Julien ZUBER (Paris, France)

• Olivier THAUNAT (CIRI, INSERM, Université Claude Bernard Lyon I, CNRS, École Normale Supérieure de Lyon, Université de Lyon, Lyon, France)
  Breaking Barriers Across Species: The Immunopathological Frontiers of Xenotransplantation
• Aurélie SANNIER (Hôpital Bichat - Claude-Bernard, Paris, France)
  Lessons from the First Human Xenotransplants

Foyer & Concorde 1&2 - Level -1 Coffee break - Visit of exhibition & Posters

PARALLEL SESSIONS

Guillaumet 1+2 - Level 2PS19 - Mastcells / Basophils

Chairs: Gaël MÉNASCHÉ (Paris, France) & Nicolas CHARLES (Paris, France)

• Sebastien TALBOT (Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden)
  Nociceptor neurons control inflammation
• Clare LLOYD (National Heart and Lung Institute, Imperial College London, London, United Kingdom)

+ Selected short oral presentations

• PS19-01 - Céline EL SAMROUT (Infinity, INSERM, Toulouse, France; 2 IRSD, INSERM, Toulouse, France)
  Non-immune function of myenteric mast cells in supporting neuronal plexus homeostasis
• PS19-02 - Geoffrey CHEMINET (Hematology Laboratory, Imagine Institute for Genetic Diseases - U1163 INSERM, Paris, France)
  Role of mast cells in bone vaso-occlusive crisis and pain of sickle cell disease
• PS19-03 - Zohra BENMESSAOUD (INSERM UMR1291 – CNRS UMR5051 - University Toulouse III, Infinity, Toulouse, France)
  A new mouse model expressing human IgE and its receptors FcεRI and CD23 predicts a superiority for ligelizumab over omalizumab in anaphylaxis

Cassiopée - Level 1PS20 - Mucosal immunology

Chairs: Klaas VAN GISBERGEN (Lisbon, Portugal) & Olivier NEYROLLES (Toulouse, France)

• Nicole JOLLER (Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland)
  Fungal infections imprint the Th17 pool by establishing a distinct memory Th17 population
• Andreas DIEFENBACH (Laboratory of Innate Immunity, Institute of Microbiology, Infectious Diseases and Immunology (I-MIDI), Berlin, Germany)

+ Selected short oral presentations

• PS20-01 - Margaux PARADIS (IPBS - CNRS, Toulouse, France)
  A TAK1-Driven NLRP1 Inflammasome Pathway Revealed by Phosphatase Targeting Environmental Toxins
• PS20-02 - Fabian GUENDEL (Microenvironment and Immunity Unit, Institut Pasteur, Paris, France)
  The Postnatal Stress Response Drives Long-Term Maladaptation of the Intestinal Epithelium via TLR3/TRIF Epigenetic Memory
• PS20-03 - Ignacio CABALLERO POSADAS (INRAE, Toxalim, Toulouse, France)
  TLR5 signaling amplifies airway epithelial cell responses to type I interferon through MyD88–JAK1 crosstalk during influenza infection in pigs

Audit. Saint-Exupéry - Level 2PS21 - Tissue homeostasis and dynamics

Chairs: Julie RIBOT (Lisbon, Portugal) & Meryem ALOULOU (Toulouse, France)

• Julie RIBOT (Gulbenkian Institute for Molecular Medicine (GIMM), Lisbon, Portugal)
  Stressing the role of γδ17 T cells at the crossroads of tissue communication and pathophysiology
• Karl BALABANIAN (Université Paris Cité, Institut de Recherche Saint-Louis, INSERM, Paris, France)
  CXCR4 signaling, a gatekeeper orchestrating the bone marrow ecosystem

+ Selected short oral presentations

• PS21-01 - Miguel MESQUITA (Gulbenkian Institute for Molecular Medicine (GIMM), Avenida Professor Egas Moniz, Oeiras, Portugal)
  Ferroptosis is a Physiologic Vulnerability of Iron-Recycling Macrophages
• PS21-02 - Dan CORRAL (INFINITY, Toulouse, France)
  Let it flow: Maternal immune regulation of lactation
• PS21-03 - Chloé MICHAUDEL (MTS - LIAA, INRAE, Gif sur Yvette Cedex, France)
  Low-dose perinatal pesticide exposure reprograms immune development in male offspring and increases susceptibility to type-2 airway inflammation

Ariane 1 - Level 1 CPS22 - CEnI General Assembly

Clinical session

PLENARY SESSION

Audit. Saint-Exupéry - Level 2SESSION 3 - Young investigators

Chairs: Marie-Astrid BOUTET (Nantes, France), Joaquin PELLEGRINI (Toulouse, France), Mehdi BENAMAR (Montpellier, France), Catarina AZEVEDO (Porto, Portugal) & Inês ALVES (Porto, Portugal)

• Thomas MARICHAL (GIGA Institute, University of Liège, Liège, Belgium)
  A deep dive into the biology of lung myeloid cells in health and disease

+ Selected short oral presentations

• P3-01 - Camille CHATELAIN (Division of Immuno-oncology, Lund Stem Cell Center, Lund University, Lund, Sweden)
  Inducing immunogenic lymphoid structures across cancers by tumor-to-dendritic cell reprogramming
• P3-02 - Ana Carolina VALENTE SANTOS CRUZ DE ARAUJO (Department of Immunology, University of São Paulo, São Paulo, São Paulo, Brazil)
  HIF-1α licenses BCG-induced trained immunity to promote pulmonary and systemic protection against Brucella abortus infection
• P3-03 - Tomás MACHADO (University of Coimbra, Center for Innovative Biomedicine and Biotechnology, Center for Neuroscience and Cell Biology, Cantanhede, Coimbra, Portugal)
  Retinoic acid modulates invariant Natural Killer T cell development and function in colon cancer

Congress Dinner