SFI-SPI 2026

Foyer & Concorde 1&2 - Level -1 Meeting registration

PLENARY SESSIONS

Audit. Saint-Exupéry - Level 2Welcome introduction

Audit. Saint-Exupéry - Level 2Keynote Lecture

Chairs: Roland LIBLAU (Toulouse, France) & Luis GRACA (Lisbon, Portugal)

• Shimon SAKAGUCHI (WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan)
  Regulatory T cells and immune tolerance

Audit. Saint-Exupéry - Level 2SESSION 1 - NeuroImmunology

Chairs: Julie RIBOT (Lisbon, Portugal) & Anne ASTIER (Toulouse, France)

• Nicolas GAUDENZIO (Infinity - Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, Inserm, CNRS, Toulouse, France)
  Fetal-maternal interface, neuroimmune circuits and chronic inflammation
• Rejane RUA (Center for Immunology of Marseille-Luminy (CIML), Marseille, France)
  Brain border myeloid cells: more than immune sentinels?

+ Selected short oral presentations

• P1-01 - Lena BOURHY (Development and Homeostasis of the Nervous System, The Francis Crick Institute, London, United Kingdom)
  Neural pathways mediating the gut-lung axis
• P1-02 - Nouha SOUFI (IPMC, CNRS, Valbonne, Provence-Alpes-Cote d'Azur, France)
  Splenic nerve stimulation protects against murine experimental autoimmune encephalomyelitis via B cell beta2-adrenergic licensing of Tregs
• P1-03 - Julien NOVARINO (CIMI-PARIS, Paris, France)
  Cancer-related pain is masked by enkephalins-producing regulatory T cells in mice

Audit. Saint-Exupéry - Level 2Industry Symposia

Chairs: Marc VOCANSON (Lyon, France) & Fatima-Ezzahra L'FAQIHI-OLIVE (Toulouse, France)

Foyer & Concorde 1&2 - Level -1Lunch - Coffee - Visit of exhibition & Posters

PARALLEL SESSIONS

PS1 - Macrophages and dendritic cells

Chairs: Sandrine HENRI (Tours, France) & Nathalie BENDRISS-VERMARE (lyon, France)

• Florent GINHOUX (Institut Gustave-Roussy, Villejuif, France)
• Ana-Maria LENNON-DUMENIL (Institut Curie, PSL Research University, INSERM U932, Paris, France)
  Environment patrolling by immune phagocytes

+ Selected short oral presentations

• PS1-01 - Clara TAFFONI (IRMB, INSERM U1183, Montpellier, France)
  VSIG4 licenses resident synovial macrophages to restrain inflammatory arthritis
• PS1-02 - Donia SAIB (CRCL, INSERM, LYON, France)
  Macrophage NOTCH1 signaling in pancreatic cancer : immune and stromal remodeling
• PS1-03 - Sahar SEYED HASSANTEHRANI (Immunoregulation Lab, Champalimaud Foundation, Champalimaud Centre for the Unknown, Lisbon, Portugal)
  Infection-specific regulation of cDC2 poiesis shapes dendritic cell subset responses

PS2 - Inborn errors in immunity

Chairs: Charline MIOT (Angers, France) & Emmanuel MARTIN (Paris, France)

• Sylvain LATOUR (Inserm - Institut Imagine, Paris, France)
  Inborn errors of immunity predisposing to severe Epstein Barr infection diseases
• Paula VIDEIRA (UCIBIO - NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal)
  GlycoImmune pathways as determinants of immune variability and disease susceptibility

+ Selected short oral presentations

• PS2-01 - Dimitra BOZOGLOU (INFINITy-INSERM, Toulouse, France)
  Architecture of actin networks at the T-cell synapse: impact of genetic variants in ACTB and ACTG1
• PS2-02 - Nhat Duong HO (Immunogenetics of Pediatric Autoimmune Diseases, Institute Imagine, Paris, France)
  Paradoxical Type I Interferon Activation in RELA Haploinsufficiency
• PS2-03 - Halima ZAHAR (Laboratory of Clinical Immunology, Infection, and Autoimmunity (LICIA), Faculty of Medicine and Pharmacy in Casablanca, Casablanca, Morocco)
  Clinical Spectrum of Chronic granulomatous disease in Moroccan Children: A Retrospective Cohort of 55 Patients

PS3 - Vaccinology

Chairs: Anne-Sophie BEIGNON (Paris, France) & Stéphane PAUL (Saint Etienne, France)

• Laurent REBER (Infinity -Toulouse Institute for Infectious and Inflammatory Diseases,
  University of Toulouse, Inserm, CNRS, Toulouse, France)
• Laurence ZITVOGEL (Institut Gustave-Roussy, Villejuif, France)

+ Selected short oral presentations

• PS3-01 - Fadel SAYES (Unité de Pathogénomique Mycobactérienne Intégrée, Département de Microbiologie, Institut Pasteur, Paris, France)
  Improved Immune Responses and Tuberculosis Protection by Aerosol Vaccination with rBCG expressing ESX-1 from Mycobacterium marinum
• PS3-02 - Charlotte HATEB (Université Toulouse, INFINITy, Inserm UMR1291, Toulouse, France)
  Development of an mRNA vaccine encoding the major allergen Bet v 1 to treat birch pollen allergy
• PS3-03 - Jean-Michel SALLENAVE (Immune signaling in cancer and infection, INSERM U1149, Centre for Inflammation Research, Paris, France)
  A novel cystic fibrosis-mimetic Pseudomonas auxotrophic vaccine is protective in vivo and is associated with Th17 and IgA mucosal immunity

CPS4 - Immunometabolism and its implications for practical medicine

Clinical session

Chairs: Guislaine CARCELAIN (Paris, France) & Olivier TOUTIRAIS (Caen, France)

• Antoine MARÇAIS (CIRI, Centre International de Recherche en Infectiologie, Université Claude Bernard Lyon 1, Inserm, CNRS, ENS de Lyon, Lyon, France)
  Use of carbon sources in human and murine Natural Killer cells: variations on a common theme
• Mireille LAFORGE (Université Paris Cité, NeuroDiderot, Inserm, Paris, France)
  Immunometabolism, from diagnosis to treatment: Applications to long COVID and autism spectrum disorders

PARALLEL SESSIONS

PS5 - ILC / NK

Chairs: Emilie NARNI (Marseille, France) & Martin VILLALBA (Montpellier, France)

• Sébastien VIEL (Centre International de Recherche en Infectiologie, Lyon, France)
• Sonja TUGUES (Innate Lymphoid Cells and Cancer, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland)
  Resident lymphocytes oreserve functional integrity of the lactating mammary niche

+ Selected short oral presentations

• PS5-01 - Nathalie BENDRISS-VERMARE (CISTAR team, Cancer Research Center of Lyon, Lyon, France)
  A Polyfunctional IL-33-Responsive ST2⁺NK Cell State Promotes Antitumor Immunity and Response to Immunotherapy
• PS5-02 - Juan SIENES BAILO (Immunoregulation Unit, Department of Immunology, Institut Pasteur, Université Paris Cité, Paris, France)
  IL-23 drives a pro-inflammatory state in human group 3 innate lymphoid cells (ILC3)
• PS5-03 - Mariana CARREIRA (Gulbenkian Institute for Molecular Medicine (GIMM), Lisbon, Portugal)
  CXCR3 signaling promotes Delta One T cell recruitment and antitumor efficacy in colorectal cancer

PS6 - Immunometabolism

Chairs: Anne DEJEAN (Toulouse, France) & Ricardo SILVESTRE (Braga, Portugal)

• Ricardo SILVESTRE (Life and Health Sciences Research Institute (ICVS), Braga, Portugal)
• Anne DEJEAN (Infinity -Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, Inserm, CNRS, Toulouse, France)

+ Selected short oral presentations

• PS6-01 - Loane JOLY (Laboratoire de Biologie et Modélisation de la Cellule, INSERM, CNRS, ENS-Lyon, Lyon, France)
  Mitochondrial translation is a critical regulator of CD8 T-cell homeostasis and effector responses
• PS6-02 - Nicolas SOCQUET-JUGLARD (INSERM, INFINITy, Toulouse, France; 2 CNRS, IGMM, Montpellier, France)
  CD8 T cells adjust actin remodeling to nutrient availability during migration and synapse assembly
• PS6-03 - Diogo ESTÊVÃO (Tumour and Microenvironment Interactions Group, Cancer Department, i3S-Institute for Research & Innovation in Health, Porto, Portugal)
  Lipid Droplets Shield Rectal Cancer from Radiotherapy-Induced Cell Death: A Metabolic–Immune Axis of Resistance

PS7 - T and B cell development and signaling

Chairs: Marion ESPELI (Paris, France) & Bruno SILVA-SANTOS (Lisbon, Portugal)

• Nuno ALVES (i3S - University of Porto, Porto, Portugal)
  Keeping the Thymus Young: ZFP36 RNA-Binding Proteins Sustain Thymic Epithelial Cell Function to Prevent Thymic Involution and Maintain Tolerance
• Claire LEIBLER (Université de Bordeaux, CNRS, ImmunoConcEpT, Bordeaux, France)
  B Cell Regulation through Nucleic Acid Sensing TLRs

+ Selected short oral presentations

• PS7-01 - Dunja CAPITÁN SOBRINO (INFINITy, INSERM U1291, Toulouse, France)
  HuR sustains immunoregulatory B-cell responses to limit neuroinflammation
• PS7-02 - Guilhèn PRUNIER (INFINITy, INSERM, Toulouse, France)
  ICOS, CD226 and CD2 engage non-redundant synapse remodeling programs to optimize CD8+ T cell cytotoxic activity
• PS7-03 - Ruben PINHEIRO (GIMM, Lisboa, Portugal)
  N-glycosylation controls the thymic development of perinatal gd17 T-cells by dampening TCRgd signal strength

Foyer & Concorde 1&2 - Level -1Coffee break - Visit of exhibition & Posters

PARALLEL SESSIONS

PS8 - Ageing

Chairs: Nuno ALVES (Porto, Portugal) & Victorine DOUIN (Toulouse, France)

• François TROTTEIN (Institut Pasteur, Lille, France)
• Almudena RAMIRO (CNIC - Spanish National Center for Cardiovascular Research, Madrid, Spain)

+ Selected short oral presentations

• PS8-01 - David CUNE (Service of Immunology and Allergy, Lausanne University Hospital, Lausanne, Switzerland)
  Autophagy loss in dendritic cells drives inflammatory reprogramming and CD4⁺ T-cell dysregulation during aging
• PS8-02 - João CARDEIRA DA SILVA (RESTORE Institute, Toulouse, France)
  T‑cell programs shaping post‑injury outcomes in the zebrafish heart
• PS8-03 - Inês FARIA (Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal)
  Chronic exposure to interleukin-10 drives inflammaging and accelerated tissue senescence

PS9 - Young SPI / SFI

Chairs: Fanny HIDALGO VILLEDA (Marseille, France), Alexandre PACCALET (Lyon, France), Maria LTEIF (Paris, France), Catarina RODRIGUES (Porto, Portugal) & Rita SILVA-GOMES (Lisbon, Portugal)

• Carlos Minutti (Champalimaud Foundation, Lisbon, Portugal)

PS10 - Autoimmunity and inflammatory diseases

Chairs: Anne ASTIER (Toulouse, France) & Nicolas FAZILLEAU (Toulouse, France)

• Thomas KORN (Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany)
• Daniela LATORRE (Division of Neuroscience, IRCCS San Raffaele Hospital, Milan, Italy)
  Autoreactive T Cells in inflammatory peripheral neuropathies

+ Selected short oral presentations

• PS10-01 - Inês ALVES (Immunology, Cancer and Glycomedicine, i3S - Instituto de Investigação e Inovação Saude, Porto, Portugal)
  Glycan mimicry as a key mechanism in the loss of self-tolerance: deciphering novel anti-glycan autoantibodies in lupus
• PS10-02 - Angélina MIMOUN (Infinity U1291, INSERM, Toulouse, France)
  Eomes Reprograms FoxP3⁺ Regulatory T Cells toward a Cytotoxic and Pro-inflammatory State
• PS10-03 - Yves-Marie MAGAT (UMR7355, CNRS, Orléans, France)
  NLRP6 promotes inflammation and regulated cell death through activation of the caspase-3/gasdermin E pathway in bleomycin-induced pulmonary fibrosis

Foyer & Concorde 1&2 - Level -1POSTER SESSION

Wine & Cheese