SFI-SPI 2026

Foyer & Concorde 1&2 - Level -1 Meeting registration

PLENARY SESSIONS

Audit. Saint-Exupéry - Level 2Welcome introduction

• Emmanuelle JOUANGUY - SFI President
• Bruno SILVA-SANTOS - SPI President

Audit. Saint-Exupéry - Level 2Keynote Lecture

Chairs: Roland LIBLAU (Toulouse, France) & Luis GRACA (Lisbon, Portugal)

• Shimon SAKAGUCHI (WPI Immunology Frontier Research Center, The University of Osaka, Osaka, Japan)
  Regulatory T cells and immune tolerance: therapeutic re-establishment of immune self-tolerance in autoimmune disease by targeting Treg cells

Audit. Saint-Exupéry - Level 2SESSION 1 - NeuroImmunology

Chairs: Julie RIBOT (Lisbon, Portugal) & Anne ASTIER (Toulouse, France)

• Nicolas GAUDENZIO (Infinity - Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, Inserm, CNRS, Toulouse, France)
  Fetal-maternal interface, neuroimmune circuits and chronic inflammation
• Daniela LATORRE (Division of Neuroscience, IRCCS San Raffaele Hospital, Milan, Italy)
  Autoreactive T Cells in inflammatory peripheral neuropathies

+ Selected short oral presentations

• P1-02 - Nouha SOUFI (IPMC, CNRS, Valbonne, Provence-Alpes-Cote d'Azur, France)
  Splenic nerve stimulation protects against murine experimental autoimmune encephalomyelitis via B cell beta2-adrenergic licensing of Tregs
• P1-03 - Julien NOVARINO (CIMI-PARIS, Paris, France)
  Cancer-related pain is masked by enkephalins-producing regulatory T cells in mice

Audit. Saint-Exupéry - Level 2Industry Symposium

Chairs: Marc VOCANSON (Lyon, France) & Fatima-Ezzahra L'FAQIHI-OLIVE (Toulouse, France)

• BD Biosciences
  Seeing Beyond the Spectrum: Exploring biological dimensions through spectral imaging cytometry
  Laurence DELBOS & Juliette DESFRANÇOIS (Cytocell, Nantes, France)

Audit. Saint-Exupéry - Level 2Industry Talks

Chairs: Marc VOCANSON (Lyon, France) & Fatima-Ezzahra L'FAQIHI-OLIVE (Toulouse, France)

• Cytek Biosciences
  A New Horizon: Welcome to the Borealis
  Fabien PITOISET (PhD, Field Applications Specialist, Cytek Biosciences, Amsterdam, Netherlands)

• Meso Scale Discovery (12-min presentation)
  Pushing the Boundaries of Biomarker Quantification: High Sensitivity, Multiplexing and Matrix Flexibility
  Renaud COLISSON (Field Application Scientist, Meso Scale Discovery, Rockville, United States)

• Pixelgen Technologies
  Immune Cell Surface Protein Architecture in Health and Disease - Publications and Use Case Update
  Peter DJALI (Business Development Manager, Pixelgen Technologies, Stockholm, Sweden)

• StemCell Technologies
  Automated Tissue Dissociation with STEMprep™
  Christine BARR (STEMCELL Technologies, Saint-Egrève, France)

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• Alamar Biosciences
  NULISA: An Ultrasensitive, Multiplex Immune Panel for Profiling Inflammatory and Autoimmune Disease Biomarkers
  Véronique BERCHET (Alamar Biosciences, Segrate, Italy)

Foyer & Concorde 1&2 - Level -1Lunch - Coffee - Visit of exhibition & Posters

PARALLEL SESSIONS

Audit. Saint-Exupéry - Level 2PS1 - Macrophages and dendritic cells

Chairs: Sandrine HENRI (Tours, France) & Nathalie BENDRISS-VERMARE (Lyon, France)

• Florent GINHOUX (Institut Gustave-Roussy, Villejuif, France)
• Ana-Maria LENNON-DUMENIL (Institut Curie, PSL Research University, INSERM U932, Paris, France)
  Crypt Engulfment as a Novel Antigen Sampling Mechanism in the Colon

+ Selected short oral presentations

• PS1-01 - Clara TAFFONI (IRMB, INSERM U1183, Montpellier, France)
  VSIG4 licenses resident synovial macrophages to restrain inflammatory arthritis
• PS1-02 - Donia SAIB (CRCL, INSERM, Lyon, France)
  Macrophage NOTCH1 signaling in pancreatic cancer: immune and stromal remodeling
• PS1-03 - Sahar SEYED HASSAN TEHRANI (Immunoregulation Lab, Champalimaud Foundation, Champalimaud Centre for the Unknown, Lisbon, Portugal)
  Infection-specific regulation of cDC2 poiesis shapes dendritic cell subset responses

Ariane 1 - Level 1PS2 - Inborn errors in immunity

Chairs: Charline MIOT (Angers, France) & Emmanuel MARTIN (Paris, France)

• Paula VIDEIRA (UCIBIO - NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal)
  GlycoImmune pathways as determinants of immune variability and disease susceptibility
• Sylvain LATOUR (Inserm - Institut Imagine, Paris, France)
  Inborn errors of immunity predisposing to severe Epstein Barr infection diseases

+ Selected short oral presentations

• PS2-01 - Dimitra BOZOGLOU (INFINITy-INSERM, Toulouse, France)
  Architecture of actin networks at the T-cell synapse: impact of genetic variants in ACTB and ACTG1
• PS2-02 - Nhat Duong HO (Immunogenetics of Pediatric Autoimmune Diseases, Institute Imagine, Paris, France)
  Paradoxical Type I Interferon Activation in RELA Haploinsufficiency

Guillaumet 1+2 - Level 2PS3 - Vaccinology

Chairs: Anne-Sophie BEIGNON (Paris, France) & Jean-Daniel LELIEVRE (Créteil, France)

•  Laurence ZITVOGEL (Institut Gustave-Roussy, Villejuif, France)
• Laurent REBER (Infinity -Toulouse Institute for Infectious and Inflammatory Diseases,
  University of Toulouse, Inserm, CNRS, Toulouse, France)
  Development of therapeutic vaccines for the treatment of allergic diseases

+ Selected short oral presentations

• PS3-01 - Fadel SAYES (Unité de Pathogénomique Mycobactérienne Intégrée, Département de Microbiologie, Institut Pasteur, Paris, France)
  Improved Immune Responses and Tuberculosis Protection by Aerosol Vaccination with rBCG expressing ESX-1 from Mycobacterium marinum
• PS3-02 - Charlotte HATEB (Université Toulouse, INFINITy, Inserm UMR1291, Toulouse, France)
  Development of an mRNA vaccine encoding the major allergen Bet v 1 to treat birch pollen allergy
• PS3-03 - Jean-Michel SALLENAVE (Immune signaling in cancer and infection, INSERM U1149, Centre for Inflammation Research, Paris, France)
  A novel cystic fibrosis-mimetic Pseudomonas auxotrophic vaccine is protective in vivo and is associated with Th17 and IgA mucosal immunity

Cassiopée - Level 1CPS4 - Immunometabolism and its implications for practical medicine

Clinical session

Chairs: Guislaine CARCELAIN (Paris, France) & Olivier TOUTIRAIS (Caen, France)

• Antoine MARÇAIS (CIRI, Centre International de Recherche en Infectiologie, Université Claude Bernard Lyon 1, Inserm, CNRS, ENS de Lyon, Lyon, France)
  Metabolic sensors in NK cells: can we move from basic discoveries to clinical applications?
• Mireille LAFORGE (Université Paris Cité, NeuroDiderot, Inserm, Paris, France)
  Immunometabolism, from diagnosis to treatment: Applications to long COVID and autism spectrum disorders

PARALLEL SESSIONS

Guillaumet 1+2 - Level 2PS5 - ILC / NK

Chairs: Emilie NARNI (Marseille, France) & Sophie LAFFONT-PRADINES (Toulouse, France)

• Sébastien VIEL (Centre International de Recherche en Infectiologie, Lyon, France)
  The TGF-β paradox in NK cells: from immune suppression to context-dependent functional reprogramming
• Sonja TUGUES (Innate Lymphoid Cells and Cancer, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland)
  Resident lymphocytes preserve functional integrity of the lactating mammary niche

+ Selected short oral presentations

• PS5-01 - Nathalie BENDRISS-VERMARE (CISTAR team, Cancer Research Center of Lyon, Lyon, France)
  A Polyfunctional IL-33-Responsive ST2⁺NK Cell State Promotes Antitumor Immunity and Response to Immunotherapy
• PS5-02 - Juan SIENES BAILO (Immunoregulation Unit, Department of Immunology, Institut Pasteur, Université Paris Cité, Paris, France)
  IL-23 drives a pro-inflammatory state in human group 3 innate lymphoid cells (ILC3)
• PS5-03 - Mariana CARREIRA (Gulbenkian Institute for Molecular Medicine (GIMM), Lisbon, Portugal)
  CXCR3 signaling promotes Delta One T cell recruitment and antitumor efficacy in colorectal cancer

Cassiopée - Level 1PS6 - Immunometabolism

Chairs: Anne DEJEAN (Toulouse, France) & Ricardo SILVESTRE (Braga, Portugal)

• Ricardo SILVESTRE (Life and Health Sciences Research Institute (ICVS), Braga, Portugal)
  Macrophage immunometabolism: shaping pathogen persistence and host protection
• Anne DEJEAN (Infinity -Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, Inserm, CNRS, Toulouse, France)
  Eomes drives an exhausted T helper cell lineage essential for tumor control and response to immunotherapy

+ Selected short oral presentations

• PS6-01 - Loane JOLY (Laboratoire de Biologie et Modélisation de la Cellule, INSERM, CNRS, ENS-Lyon, Lyon, France)
  Mitochondrial translation is a critical regulator of CD8 T-cell homeostasis and effector responses
• PS6-02 - Nicolas SOCQUET-JUGLARD (INSERM, INFINITy, Toulouse, France; 2 CNRS, IGMM, Montpellier, France)
  CD8 T cells adjust actin remodeling to nutrient availability during migration and synapse assembly
• PS6-03 - Diogo ESTÊVÃO (Tumour and Microenvironment Interactions Group, Cancer Department, i3S-Institute for Research & Innovation in Health, Porto, Portugal)
  Lipid Droplets Shield Rectal Cancer from Radiotherapy-Induced Cell Death: A Metabolic–Immune Axis of Resistance

Audit. Saint-Exupéry - Level 2PS7 - T and B cell development and signaling

Chairs: Marion ESPELI (Paris, France) & Bruno SILVA-SANTOS (Lisbon, Portugal)

• Nuno ALVES (i3S - University of Porto, Porto, Portugal)
  Keeping the Thymus Young: ZFP36 RNA-Binding Proteins Sustain Thymic Epithelial Cell Function to Prevent Thymic Involution and Maintain Tolerance
• Claire LEIBLER (Université de Bordeaux, CNRS, ImmunoConcEpT, Bordeaux, France)
  B Cell Regulation through Nucleic Acid Sensing TLRs

+ Selected short oral presentations

• PS7-01 - Dunja CAPITÁN SOBRINO (INFINITy, INSERM U1291, Toulouse, France)
  HuR sustains immunoregulatory B-cell responses to limit neuroinflammation
• PS7-02 - Guilhèn PRUNIER (INFINITy, INSERM, Toulouse, France)
  ICOS, CD226 and CD2 engage non-redundant synapse remodeling programs to optimize CD8+ T cell cytotoxic activity
• PS7-03 - Ruben PINHEIRO (GIMM, Lisboa, Portugal)
  N-glycosylation controls the thymic development of perinatal gd17 T-cells by dampening TCRgd signal strength

Foyer & Concorde 1&2 - Level -1Coffee break - Visit of exhibition & Posters

PARALLEL SESSIONS

Guillaumet 1+2 - Level 2PS8 - Ageing

Chairs: Nuno ALVES (Porto, Portugal) & Victorine DOUIN (Toulouse, France)

• François TROTTEIN (Institut Pasteur, Lille, France)
  Aging and respiratory infections: cellular senescence, gut dysbiosis, and beyond
• Almudena RAMIRO (CNIC - Spanish National Center for Cardiovascular Research, Madrid, Spain)
  Understanding the origin of autoreactive antbodies in atherosclerosis

+ Selected short oral presentations

• PS8-01 - David CUNE (Service of Immunology and Allergy, Lausanne University Hospital, Lausanne, Switzerland)
  Autophagy loss in dendritic cells drives inflammatory reprogramming and CD4⁺ T-cell dysregulation during aging
• PS8-02 - João CARDEIRA DA SILVA (RESTORE Institute, Toulouse, France)
  T‑cell programs shaping post‑injury outcomes in the zebrafish heart
• PS8-03 - Inês FARIA (Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal)
  Chronic exposure to interleukin-10 drives inflammaging and accelerated tissue senescence

Cassiopée - Level 1PS9 - Young SPI / SFI

Chairs: Fanny HIDALGO VILLEDA (Marseille, France), Maria LTEIF (Paris, France), Catarina RODRIGUES (Porto, Portugal) & Rita SILVA-GOMES (Lisbon, Portugal)

• Carlos MINUTTI (Champalimaud Foundation, Lisbon, Portugal)
  The Academic Path: The Bad, the Good, and the Pretty

Audit. Saint-Exupéry - Level 2PS10 - Autoimmunity and inflammatory diseases

Chairs: Anne ASTIER (Toulouse, France) & Nicolas FAZILLEAU (Toulouse, France)

• Thomas KORN (Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany)
  Compartmentalized regulation of CNS autoimmunity
• Rejane RUA (Center for Immunology of Marseille-Luminy (CIML), Marseille, France)
  Brain border myeloid cells: more than immune sentinels?

+ Selected short oral presentations

• PS10-01 - Inês ALVES (Immunology, Cancer and Glycomedicine, i3S - Instituto de Investigação e Inovação Saude, Porto, Portugal)
  Glycan mimicry as a key mechanism in the loss of self-tolerance: deciphering novel anti-glycan autoantibodies in lupus
• PS10-02 - Angélina MIMOUN (Infinity U1291, INSERM, Toulouse, France)
  Eomes Reprograms FoxP3⁺ Regulatory T Cells toward a Cytotoxic and Pro-inflammatory State
• PS10-03 - Yves-Marie MAGAT (UMR7355, CNRS, Orléans, France)
  NLRP6 promotes inflammation and regulated cell death through activation of the caspase-3/gasdermin E pathway in bleomycin-induced pulmonary fibrosis

Foyer & Concorde 1&2 - Level -1POSTER SESSION 1 - odd-numbered

Foyer & Concorde 1&2 - Level -1Welcome Cocktail

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