SFI 2025

12-14 November 2025 - Cité des sciences et de l’industrie, Paris, France

Bandeau - SFI 2025
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Wednesday 12 November

08:00-09:30

Foyer - Level S1 Meeting registration


PLENARY SESSIONS
09:30-09:45

Amphi. Gaston Berger - Level S2Welcome Introduction

  • Daniel OLIVE - SFI President

09:45-10:30

Amphi. Gaston Berger - Level S2Pierre Grabar* Keynote Lecture

* Cofounder and 1st President of the SFI

Chair: Emmanuelle JOUANGUY (Paris, France)

  • Jean-Laurent CASANOVA (Human Genetics of Infectious diseases, Rockefeller University, New York, USA, Imagine institute, Necker Hospital for Sick Children, Paris, France)
    Human genetics of infectious diseases

10:30-11:30

Amphi. Gaston Berger - Level S2SESSION 1 - Tolerance / Autoimmunity

Chairs: Marianne BURBAGE (Paris, France) & Anne ASTIER (Toulouse, France)

  • Carola VINUESA (The Francis Crick Institute, London, UK)
    Title upcoming
  • Magali IRLA (Immune tolerance and T cell differentiation, CIML, Marseille, France)
    Thymic Central T Cell Tolerance: From Age-Related Involution to Immune Rejuvenation

Selected short oral presentations

  • P1-01 - Meryem ALOULOU (INFINITY, INSERM UMR1291 – CNRS UMR5051 – University of Toulouse, Toulouse, France)
    Follicular Regulatory T Cells: Unexpected Allies of Neuroinflammation
  • P1-02 - Claire SOUDAIS (UMR1163, Institut Imagine, Paris, France)
    Inhibition of the CTP synthase 1 prevents GVHD and delays skin graft rejection revealing distinct allo-T-cell responses
  • P1-03 - Emeline PAPILLON (U932, Institut Curie, Paris, France)
    How do transposable elements shape T cell thymic selection?

11:30-12:30

Foyers - Levels S2-S3POSTER SESSION 1 - odd-numbered


11:30-12:30

Foyer - Level S2E-POSTER SESSION 1

Chair: Fabienne HASPOT (Nantes, France)

See the list of posters presented and the order of presentation


11:30-12:30

Foyer - Level S2E-POSTER SESSION 2

Chair: Rami BECHARA (Le Kremlin-Bicêtre, France)

See the list of posters presented and the order of presentation


12:30-14:00

Foyers - Levels S1-S2-S3 Lunch - Coffee - Visit of exhibition & Posters


14:00-17:00

Salle Louis Armand Ouest - Level S3JOURNÉE FÉDÉRATION D’IMMUNOLOGIE MÉDICALE

  

Logo fede-immonologieThérapies cellulaires innovantes dans la prévention de la GVH après allogreffe de cellules souches hématopoiétiques

Modérateurs : Stéphanie NGUYEN (Paris, France) & Jean-Hugues DALLE (Paris, France)

  • Étienne DAGUINDAU (Besançon, France)
    Logo MedacLogo SonyPhysiopathologie de la GVH aigue et prévention en pratique courante
  • Mathieu LECLERC (Créteil, France)
    T régulateurs en prévention de la GVH chez l’homme
  • Federico SIMONETTA (Genève, Suisse)
    Lymphocytes iNKT murins et modulation des effets GVH/GVL
  • Marie-Thérèse RUBIO (Nancy, France)
    Lymphocytes iNKT humains et leur développement clinique dans l’allogreffe de CSH
  • Maud D’AVENI-PINEY (Nancy, France)
    Cellules myéloides suppressives (MDSC) dans la greffe de CSH
  • Cécile POCHON (Nancy, France)
    Cellules souches stromales mésenchymateuses (CSM) : comment optimiser leur utilisation pour prévenir la GVH ?
  • Table ronde

PARALLEL SESSIONS
14:00-15:30

Salle Louis Armand Est - Level S3SP1 - Germinal Centers Club

Chairs: Carole LE COZ (Toulouse, France) & Céline DELALOY (Rennes, France)

  • Pierre MILPIED (Integrative B cell immunology, CIML, Marseille, France)
    Pre-plasma cells proliferate and differentiate at the germinal center-medulla interface of antigen-draining lymph nodes
  • Johanne JACOBSEN (Rikshospitalet, University of Oslo, Norway)
    Title upcoming

Selected short oral presentations

  • SP1-01 - Yoann MISSOLO (INSERM U1330, Institut Curie, Paris, France)
    CD4+ T Cells Response to Tumor Invasion in Lymph Nodes
  • SP1-02 - Emma VALDEVIT (Toulouse institute for infectious and inflammatory diseases, Toulouse, France)
    Human T follicular regulatory cells are composed by two layers of heterogeneity
  • SP1-03 - Robert PHILIPPE (Laboratoire Adhesion et Inflammation, INSERM-CNRS-Aix-Marseille Université, Marseille, France)
    Mechanical force resistance rather than affinity as a selection factor driving antibody maturation in secondary lymphoid tissues

14:00-15:30

Amphi. Gaston Berger - Level S2SP2 - Inborn errors of immunity Club

Chairs: Emmanuel MARTIN (Paris, France) & Tom LE VOYER (Paris, France)

  • Vivien BÉZIAT (Human Genetics of Infectious diseases, Imagine institute, Paris, France)
    Genetic Determinants of Severe Cutaneous Oncoviral Infections
  • Filomeen HAERYNCK (University of Ghent, Belgium)
    Title upcoming

Selected short oral presentations

  • SP2-04 - Jean Sebastien DIANA (Department of Biotherapy, Necker Hospital (APHP), Paris, France)
    Gene therapy for Artemis deficiency: the results of the French ARTEGENE 2 Phase I/II clinical trial
  • SP2-05 - Hailun LI (HGID, Institut Imagine, Paris, France)
    Syndromic severe combined immunodeficiency in children with a complete form of inherited JAK1 deficiency
  • SP2-06 - Nicolas AYAS (U1151, Institut Necker Enfants Malades, Paris, France)
    A neomorphicIRF4 variant disrupts human Treg biology in Primary Antibody deficiency-associated IBD

14:00-15:30

Salle 2 - Level S3SP3 - Career development (Young) Club

Chairs: Marie-Astrid BOUTET (Nantes, France) & Joaquin PELLEGRINI (France)

  • Julie FLOCH (Association Bernard Gregory (ABG) - Responsable Formation et Accompagnement) & Shahul MOUHAMAD (Miltenyi Biotec - Marketing manager)
    A wide range of opportunities for PhDs
  • Paola GARDELLIN (Présidente fondatrice de REVEALIS - Coach professionnel)
    From researcher to entrepreneur: is Women Leadership different from Men’s?
  • Renaud POURPRE (Fondateur du collectif Exaltia - Science communicator)
    Tips for becoming a part-time science communicator
  • Round-table discussion: Julie FLOCH, Paola GARDELLIN, Renaud POURPRE & Shahul MOUHAMAD

PARALLEL SESSIONS
15:30-17:00

Amphi. Gaston Berger - Level S2SP4 - Immunometabolism

Chairs: Mehdi BENAMAR (Boston, USA) & Romain RONCAGALLI (Marseille, France)

  • Stefanie WCULEK (Institute for Research in Biomedicine, Barcelona, Spain)
    How innate immune cells adapt to environment and function: diverse tales of mitochondria
  • Linda SINCLAIR (University of Dundee, UK)
    Fuelling T cells -> Proteostasis in T cells

Selected short oral presentations

  • SP4-07 - Axelle PENC (Institut Necker Enfants Malades, Paris, France)
    The innate immune system contributes to the development of Pompe disease and represents an efficient therapeutic target
  • SP4-08 - Bastien AZNAR (Institut Necker Enfants-Malades, Paris, France)
    The Histone Demethylase KDM6B Governs the LYVE1+ Perivascular Macrophage Phenotype to Control Adipose Tissue Expandability
  • SP4-09 - Margaux SARRET (Sorbonne Université, Inserm U1135, CIMI, Paris, France)
    Age-Dependent Immunometabolism: Energetic Profiles of Lymphocytes and Monocytes

15:30-17:00

Salle Louis Armand Est - Level S3SP5 - Aging/senescence

Chairs: Bruno LUCAS (Paris, France) & Julie DÉCHANET-MERVILLE (Bordeaux, France)

  • Jörg GORONZY (University of Stanford, CA, USA)
    TCF1 and HELIOS – Goddesses of T-cell youth
  • María MITTELBRUNN (Centro de Biologia Molecular - UAM, Madrid, Spain)
    Unlocking healthy aging through the immune system

Selected short oral presentations

  • SP5-10 - Romain TORRES (INFINITY, INSERM UMR1291, Toulouse, France)
    Aging predisposes naive CD4+ T cell to a pro-inflammatory Th1 fate
  • SP5-11 - Bruno MARTIN (Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France)
    IFN-α-driven down-regulation of Foxo1 induces functional remodeling of the peripheral γδ T-cell compartment with Age
  • SP5-12 - Manon CHAUVIN (Sorbonne Université, Inserm U1135, CIMI-Paris, Paris, France)
    From Immune Activation to Immune Decline: Neopterin in the Aging Process

17:00-17:45

Foyers - Levels S1-S2-S3Coffee break - Visit of exhibition - Posters


PARALLEL SESSIONS
17:45-19:15

Salle Louis Armand Est - Level S3SP6 - Neuroimmunology

Chairs: Nicolas FAZILLEAU (Toulouse, France) & Anne ASTIER (Toulouse, France)

  • Marina RUBIO (Physiopathology and Imaging of Neurological Disorders, GIP Cyceron, Normandie University, Caen, France)
    BAMs take the lead: orchestrating neuroinflammation after ischemic stroke
  • Mikael SIMONS (Institute of Neuronal Cell Biology, Munich, Germany)
    Myelin pathology & neuroinflammation in the CNS

Selected short oral presentations

  • SP6-13 - Mehdi BENAMAR (Division of Immunology, Boston Children’s Hospital, Boston, Massachusetts, USA)
    Notch3+ Regulatory T cells Drive Autoimmune Neuroinflammation in Multiple Sclerosis
  • SP6-14 - Irini EVNOUCHIDOU (Centre de Recherche sur l’Inflammation, INSERM U1149, Université Paris Cité, Paris, France)
    A new transcription factor regulating neuroinflammation
  • SP6-15 - Nicolas BLANCHARD (Inserm UMR1291 - CNRS UMR5051 - University of Toulouse, Toulouse Institute for Infectious and Inflammatory diseases - Infinity, Toulouse, France)
    Immune evasion by Toxoplasma gondii through epigenetic suppression of neuronal MHC I presentation

17:45-19:15

Amphi. Gaston Berger - Level S2SP7 - TCR/BCR Signalisation

Chairs: Laurence BATAILLE (Paris, France) & Romain RONCAGALLI (Marseille, France)

  • Renaud LESOURNE (Integrative mapping of lymphocyte signaling and function, Toulouse Institute for Infectious and Inflammatory Diseases, Toulouse, France)
    Fine tuning T cell responses through checkpoint regulation and diversification
  • Pieta MATTILA (University of Turku, Finland)
    Septin7 regulates the formation of the B cell immune synapse and B cell responses

Selected short oral presentations

  • SP7-16 - Hermine FERRAN (U932, Institut Curie, Paris, France)
    The MARK2 kinase acts as a gatekeeper of CD28-dependent co-stimulation in T cells
  • SP7-17 - Audrey PAGE (Centre de Recherche en Cancérologie de Lyon (CRCL), Lyon, France)
    Disruption of Intracellular Immune Checkpoints Lowers the Activation Threshold of TCR-T Cells
  • SP7-18 - Manuel D. DIAZ-MUNOZ (Inserm U1291, Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse, France)
    Post-transcriptional regulation of the B-cell receptor is instrumental for innate B cell maintenance and regulatory function