Thursday 13 November
PARALLEL SESSIONS
Salle Louis Armand Est - Level S3SP8 - Tissue barrier
Chairs: François LEGOUX (Rennes, France) & Kamel BENLAGHA (Paris, France)
- Eduardo VILLABLANCA (Karolinska Institute, Stockholm, Sweden)
 Spatiotemporal Dynamics of Intestinal Inflammation and Healing
- Antoine	ROQUILLY (Center for Research in Transplantation and Translational Immunology, Nantes, France)
 Differences in spatiotemporal adaptation of ontogenically distinct alveolar macrophages regulate the response to interferon during respiratory sepsis
Selected short oral presentations
- SP8-19 - Hugo SANTENAC (Inserm-Infinity, Toulouse, France)
 Neonatal regulatory T cells persist into adulthood across multiple tissues with high enrichment in the skin
- SP8-20 - Marco RODARI (Laboratory of Intestinal Immunity, Institut Imagine, Paris, France)
 Importin 8-Dependent TGF-Βeta signaling shapes gut homeostasis via control of regulatory T Cell differentiation
- SP8-21 - Valentina VENZIN (Meta-organisme Unit, Institut Pasteur, Paris, France)
 CD4+ T cells license Kupffer cells to produce IL-27 and reverse the CD8+ T cell dysfunction induced by hepatocellular priming
Amphi. Gaston Berger - Level S2SP9 - Myeloid cells
Chairs: Sandrine HENRI (Tours, France) & Nathalie CHAPUT (Villejuif, France)
- Élodie	SEGURA (Institut Necker Enfants Malades, INSERM U1151, Paris)
 Mechanical stress promotes skin immune surveillance by myeloid cells and vaccine efficiency
- Caetano REIS E SOUSA (The Francis Crick Institute, London, UK)
 Dendritic cells in immunity to cancer
Selected short oral presentations
- SP9-22 - Aurélie SEMERVIL (Institut Pasteur, Paris, France)
 Immune checkpoint inhibition immunotherapy promotes dendritic cell development from early multipotent hematopoietic progenitors
- SP9-23 - Pierre DUQUESNE (U1163, Institut Imagine, Paris, France)
 Kinesin-1 regulates dendritic cell migration by coordinating cytoskeletal crosstalk via the modulation of RhoA activity
- SP9-24 - Tarek CHEKROUNE (UMR 7355, CNRS, Orléans, France)
 Autophagy in macrophages as a player of cell death in LPS-induced lethal shock
Salle Louis Armand Ouest - Level S3Session Médicale
SP10 - Neuroimmunologie
 
 
        
                 Modérateurs :  Alexandre JENTZER (Montpellier, France), Chloé BOST (Toulouse, France) & Delphine STERLIN (Paris, France)
Modérateurs :  Alexandre JENTZER (Montpellier, France), Chloé BOST (Toulouse, France) & Delphine STERLIN (Paris, France)
 Kumaran DEIVA (Hôpital Bicêtre, Le Kremlin-Bicêtre, France) Kumaran DEIVA (Hôpital Bicêtre, Le Kremlin-Bicêtre, France)
 Translating immunological mechanisms in pediatric MOG antibodies associated diseases to clinical practice
 Jérôme DEVAUX (Centre de Recherche en Neurobiologie et Neurophysiologie, Marseille, France) Jérôme DEVAUX (Centre de Recherche en Neurobiologie et Neurophysiologie, Marseille, France)
 Immunology and physiopathology of autoimmune nodopathy
Selected short oral presentations
- SP10-25 -	Anne ASTIER (INSERM U1291 Infinity, Toulouse, France)
 A Sex Bias in Tr1 Differentiation in Multiple Sclerosis
- SP10-26 - Raphaelle LAUTRAITE (mmunology, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne Université, Paris, France)
 Lambda and Kappa Free Light Chains in CSF: An Alternative to OCB in Pediatric Neuroinflammatory Diseases
- SP10-27 - Delphine STERLIN (Département d’Immunologie, Hôpital La Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris, Paris, France)
 Distinct IgM N-Glycosylation Patterns Drive Pathogenicity in Anti-MAG Neuropathy
Foyers - Levels S1-S2-S3Coffee break - Visit of exhibition - Posters
PLENARY SESSIONS
Amphi. Gaston Berger - Level S2SESSION 2 - Cancer immunology
Chairs: Julien MARIE (Lyon, France) & Daniel OLIVE (Marseille, France)
- Clotilde	THERY	(Immune response to cancer, Curie Institute, Paris, France)
 Tumor-immune system cross-talk: different roles of soluble secreted factors and extracellular vesicles
- Daniela	THOMMEN (Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands)
 Spatiotemporal dynamics of immunotherapy responses in cancer tissues
Selected short oral presentations
- P2-04 - Nataliya YEREMENKO (Center for Research in Transplantation and Translational Immunology, UMR1064, University of Nantes, Nantes, France)
 Targeting the BOB1-OCT2 Axis: A Novel Therapeutic Strategy for Mature B-Cell Malignancies
- P2-05 - Théotime LAVERGNE (Inserm-Infinity, Toulouse, France)
 Stability of Foxp3+ regulatory T cells in tumors
- P2-06 - Fabienne HASPOT (INSERM 1064, CR2TI, Nantes, France)
 An unexpected tumor escape mechanism mediated by HHLA2
Amphi. Gaston Berger - Level S2Industry Symposia
Chairs: TBC
 Euroimmun Euroimmun
 Benoît CANTARELLI (Euroimmun)
 Anti-neuronal auto-antibodies : News in diagnostic testing with cell-based assays
 CeGaT CeGaT
 Lara EL BAZZAL (CeGaT)
 CeGaT in precision immunology: lifting immune research with sequencing expertise and
 end-to-end workflows
 BD Biosciences BD Biosciences
 Régis BUCHAILLE (BD Biosciences)
 Combining spectral and imaging technologies: Shortening time to insight for deep biology research
 Agilent Technologies Agilent Technologies
 Hervé CHAULET (Agilent Technologies) & Jérôme DARAKDJIAN (Agilent Technologies)
 Complementary technologies for your fundamental, applied and medical research in immunology
 Pixelgen Technologies Pixelgen Technologies
 Peter DJALI (Pixelgen)
 Using Pixelgen's Cell Surface Protein Interactomics Assay to Better Understand Immune
 Cell Behaviour and Clinical Response
Foyers - Levels S1-S2-S3 Lunch - Coffee - Visit of exhibition & Posters
Foyers - Levels S2-S3POSTER SESSION 2 - even-numbered
Foyer - Level S2E-POSTER SESSION 3
Chair: Fabienne HASPOT (Nantes, France)
See the list of posters presented and the order of presentation
Foyer - Level S2E-POSTER SESSION 4
Chair: Mathieu CHEVALIER (Paris, France)
See the list of posters presented and the order of presentation
PARALLEL SESSIONS
Salle 2 - Level S3SP11 - Mastocytes and Basophils Club
Chairs: Gaël MÉNASCHÉ (Paris, France) & Nicolas CHARLES (Paris, France)
- Tim LÄMMERMANN (Center of Molecular Biology of Inflammation (ZMBE), University of Münster, Germany)
 Mast cells – unique cells among immune cells
- Martijn SCHUIJS (Immunoregulation and Mucosal Immunology, Cancer Research Institute Ghent, Belgium)
 Basophils as Gatekeepers: Amplifying Asthma Through IL-33-Driven Th2 Infiltration
Selected short oral presentations
- SP11-28 - Jasper KAMPHUIS (INSERM UMR1291 INFINITy, Toulouse, France)
 Dietary fermentable carbohydrates promote mucosal mast cell-dependent type 2 immune responses and intestinal pain
- SP11-29 - Morgane THAMINY (Centre de Recherche sur l’inflammation (CRI), INSERM UMR 1149 CNRS EMR 8252, Paris, France)
 IL-4 expressing basophils influence the B cell extrafollicular pathway during lupus
- SP11-30 - Charlotte HATEB (Laurent Reber’s team, Infinity (Inserm), Toulouse, France)
 Development of mRNA-LNP encoding the major allergen Bet v 1 to treat birch pollen allergy
Amphi. Gaston Berger - Level S2SP12 - Vaccinology Club
  Chairs: Anne-Sophie BEIGNON (Paris, France) & Jean-Daniel LELIÈVRE (Paris, France)
Chairs: Anne-Sophie BEIGNON (Paris, France) & Jean-Daniel LELIÈVRE (Paris, France)
- Karin LORÉ (Karolina Institute, Stockholm, Sweden)
 Understanding immunological mechanisms of mRNA vaccination compared to conventional platforms
- Lisa CHAKRABARTI (Virus and immunity, Pasteur Institute, Paris, France)
 Development of lymphoid organ-on-chip models to evaluate vaccine immunogenicity
Selected short oral presentations
- SP12-31 - Mathieu EPARDAUD (UMR ISP Université-INRAE 1282/BioMAP, INRAe, Tours, Fance)
 A Novel Intranasal Subunit Vaccine Platform Achieves Broad Protection and Transmission Blocking: Demonstrated Against SARS-CoV-2
- SP12-32 - Manon BROUTIN (Auto-Immune and Immune B cells, Institut Necker Enfants Malades, INSERM U1151/CNRS UMR 8253, Paris, France)
 Beta spike vaccine quaternary structure reshapes the memory B-Cell repertoire by hiding cryptic epitopes
- SP12-33 - Flora BATOUL (UPSaclay, Inserm, CEA, IDMIT/IMVA-HB/UMRS1184, Fontenay-aux-Roses, France)
 Trained immunity induction by a recombinant BCG expressing ESX-1 of Mycobacterium Marinum in non-human primates
Salle Louis Armand Est - Level S3SP13 - Immunopediatry Club
Chairs: Rami BECHARA (Le Kremlin-Bicêtre, France) & Nabila SEDDIKI (Paris, France)
- Alexandre BELOT (Genetic anomalies in autoimmunity, National Center of Research in Infectiology, Lyon, France)
 Unraveling Monogenic Lupus: From Immune Tolerance to Precision Therapy
- Liza Konnikova (Yale University, New Haven, United States)
 Early life immunity, small but mighty
Selected short oral presentations
- SP13-34 - Claire-Maëlle FOVET (IMVA-HB/IDMIT, Université Paris-Saclay, Inserm, CEA, Fontenay-aux-Roses, France)
 The benefit of maternal vaccination and immunity transfer in a neonatal macaque model of SARS-CoV-2 infection
- SP13-35 - Thomas MOREAU (Translational Immunology Unit, Institut Pasteur, Paris, France)
 Dysregulation of the TLR3/MDA5 pathway and increased seropositivity in juvenile dermatomyositis patients implicates viral infection as a disease trigger
- SP13-36 - Adrien CAFFIERS (U1016, Institut Cochin, Paris, France)
 Microbiota from type 1 diabetic children induces MAIT cell dysfunction and alters intestinal mucosa
Salle Louis Armand Ouest - Level S3Session Médicale
SP14 - Anticorps bispécifiques
 
 
        
         Modérateurs :  Jérôme MARTIN (Nantes, France) & Hervé WATIER (Tours, France)
Modérateurs :  Jérôme MARTIN (Nantes, France) & Hervé WATIER (Tours, France)
- Cyrille TOUZEAU (CHU, Nantes, France)
 Thérapies redirigeant les cellules T dans le myélome multiple
- Éric VIVIER (CIML, Marseille, France)
 Depleting antibodies in cancer therapy
Selected short oral presentations
- SP14-37 - Nicolas DEREDEC (Team normal and pathological hematopoiesis, Cochin Institute, Paris, France)
 Early T cells changes predict the response to CD3xBCMA bispecific antibodies in blood cancer
- SP14-38 - Julia	ETERRADOSSI (Cancer Immune Surveillance and Therapeutic Targeting Team - U1052, Centre de Recherche en Cancérologie de Lyon, Lyon, France)
 Evaluation of CCR8 as an anchor for the development of therapies specific to T regulatory lymphocytes infiltrating the tumor microenvironment in solid cancers
- SP14-39 - Théo LABOURET (U1236 - MOBIDIC, Université de Rennes, INSERM, Rennes, France)
 Chronically stimulated T cells exhibit a dysfunctional transcriptional program associated with a reduced effector function in response to bispecific antibodies
Foyers - Levels S1-S2-S3Coffee break - Visit of exhibition - Posters
PARALLEL SESSIONS
Amphi. Gaston Berger - Level S2SP15 - Signalisation / Inflammation
Chairs: Charline MIOT (Angers, France) & Julien MARIE (Lyon, France)
- Bénédicte PY (NLRP3 inflammasome and immune response to sepsis, National Center of Research in Infectiology, Lyon, France)
 Functional analysis of NLRP3 natural variants for the diagnosis of autoinflammatory diseases, and the understanding of inflammasome regulation
- Jean-Philippe	GIRARD (IPBS-CNRS, University of Toulouse, Toulouse, France)
 From IL-33 to TL1A: role of alarmin cytokines in the initiation of allergic airway inflammation
Selected short oral presentations
- SP15-40 - Dhouha MSALBI (U1262 CRIBL, University of limoges, INSERM, limoges, France)
 Soluble CD95L triggers Caspase-10-driven reactive oxygen species production in neutrophils and aggravates anti-neutrophil cytoplasmic antibody-vasculitis
- SP15-41 - Oumaima BAAZIZ (Leukomotion Lab, Institut Necker Enfants Malades, Paris, France)
 Extracellular matrix density controls PD-1 organization and T cell migration in 3D
- SP15-42 - Saniya KARI (INSERM UMR1291 12 – CNRS UMR5051, Université de Toulouse, Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse, France)
 The multiple sclerosis associated CD226 risk variant alters vitamin D-induced human type I regulatory T cell differentiation by impairing LFA-1 activation
Salle Louis Armand Est - Level S3SP16 - Host-pathogen interactions
Chairs: Julie DÉCHANET-MERVILLE (Bordeaux, France) & Alice KOENIG (Lyon, France)
- Victor APPAY (Vulnerability and ageing of the immune system, ImmunoConcept, Bordeaux, France)
 Rejuvenation of CD8+ T cell responses in long-term treated people with HIV
- Sylvain	LATOUR (Lymphocyte activation and susceptibility to EBV, Imagine Institute, Necker Hospital for Sick Children, Paris, France)
 Role of IL-27 in immunity to Epstein-Barr infection
Selected short oral presentations
- SP16-43 - Hannah KAMINSKI (Bordeaux University Hospital, Bordeaux, France)
 Features of naive gamma delta T cells responding to CMV in human
- SP16-44 - Jérémie POSCHMANN (Université de Nantes, Nantes, France)
 PU.1 Shapes Host Epigenetic Responses to Mycobacterium tuberculosis and Represents a Target for Host Directed Therapy
- SP16-45 - Joaquin PELLEGRINI (Centre d’Immunologie de Marseille-Luminy (CIML), Aix Marseille Université, CNRS, Inserm, Marseille, France)
 SLAM family receptors: emerging regulators of human plasmacytoid dendritic cell responses to intracellular bacteria
Salle Louis Armand Ouest - Level S3Session Médicale
SP17 - Auto-anticorps anti-cytokines
 
 
        
         Modérateur : Régis JOSIEN (Nantes, France)
Modérateur : Régis JOSIEN (Nantes, France)
- Frédéric COUTANT (CHU Lyon-Sud, Pierre-Bénite, France)
 Facilitating autoantibodies to IL-17: unveiling a novel mechanism of cytokine modulation
- Paul BASTARD (Paris, France)
 Ouroboros - immunity against immunity
 CEnI General Assembly
CEnI General Assembly
 
        
       PLENARY SESSION
Amphi. Gaston Berger - Level S2SESSION 3 - Young investigators


Chairs: Mehdi BENAMAR (Boston, USA), Saniya KARI (Paris, France) & 
Alexandre PACCALET (Lyon, France)
- Achille BROGGI (Innate immunity at mucosal sites, CIML, Marseille, France)
 Interfering with mucosal homeostasis, type III IFN induce pyroptosis in IECs and impair mucosal repair
Selected short oral presentations
- P3-07 - Rodrigo de OLIVEIRA FORMIGA (Centre de Recherche Saint-Antoine, Sorbonne Université, Paris, France)
 Cadaverine, a gut-derived polyamine, regulates macrophage immunometabolism and impacts colon inflammation in a context-dependent manner
- P3-08 - Feriel REBHI (Institut Necker Enfants Malades, Paris, France)
 The secretory leukocyte protease inhibitor controls the development of Sjögren’s syndrome by regulating the function of neutrophils in the salivary glands
- P3-09 - Nainisha SHAH (Pathophysiology and Immunotherapy of inflammatory diseases, INSERM-IRMB, Montpellier, France)
 The plasticity of human FOXP3+ Tregs in rheumatoid arthritis synovial fluid
- Young researcher Article Prize annoucement
 
    
  