Webinar EBCnet Forum 2021

30 June - 2 July 2021, France

Bandeau - Webinar EBCnet Forum 2021

Program Wednesday 30 June

09:00-09:15

Opening of the 3rd EBCNet Forum

Thierry Defrance and Hans-Martin Jäck


09:20-10:40

Session #1. B cell memory/B cell subsets

Talk participants

Chairs: Michel Cogné & Marc Seifert

09:20-09:40
  • Most isotype switched memory B cells reside in bone marrow or spleen
    Marta Ferreira-Gomes (Deutsches Rheuma-Forschungszentrum (DRFZ), an Institute of the Leibniz Association, Berlin, Germany)

09:40-10:00
  • Human memory B cell dynamics in blood and spleen change with age
    Artur Kibler (Institute of Cell Biology, University of Duisburg-Essen, Essen, Germany)

10:00-10:20
  • Diversity of memory B cells repertoire cope with SARS-CoV2 variants after mRNA vaccination in naïve and recovered individuals
    Matthieu Mahévas (Institut Necker Enfants Malades (INEM), INSERM U1151/CNRS UMS 8253, Université de Paris, Paris, France)

10:20-10:40
  • Persistence of functional memory B cells recognizing SARS-CoV-2 variants despite loss of specific IgG
    Stephan Winklmeier (Institute of Clinical Neuroimmunology, University Hospital, LMU Munich, Munich, Germany)

10:40-10:47

Sponsor - Miltenyi Biotec

  • Logo MiltenyiBiotec SARS-CoV-2 specific B cells and antibodies Analysis by Miltenyi Biotec
    Shahul Mouhamad - Miltenyi Biotec

10:47-11:00

Break


11:00-12:20

Session #1 (continued). B cell memory/B cell subsets

Talk participants

Chairs: Pierre Bruhns & Deborah Dunn-Walters

11:00-11:20
  • VAST: a novel and versatile vaccination platform that induces robust and durable antibody responses
    Paraskevi Vlachou (D150, German Cancer Research Center (DKFZ), Heidelberg, Germany)

11:20-11:40
  • Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways
    Alexander Stewart (School of Biosciences and Medicine, University of Surrey, Guildford, UK)

11:40-12:00
  • T-bet+ B cells infiltrating the human brain: from peripheral induction to local effector function
    Marvin M. van Luijn (Department of Immunology, MS Center ErasMS, Erasmus MC, Rotterdam, The Netherlands)

12:00-12:20
  • Phenotypic and functional division of human Bregs in CD45lo and CD45hi B cells and their dependence on Btk and mTOR
    Vassilios Lougaris (Pediatrics Clinic and Institute of Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST - Spedali Civili of Brescia, Brescia, Italy)

12:20-12:27

Sponsor - Stemcell

  • Logo Stemcell Tools for B cell Research
    Graeme Milton - Senior European Market Development Manager, Immunology

12:27-14:00

Lunch


14:00-15:40

Session #2. B cell development/B cell neoplasia

Talk participants

Chairs: Marta Rizzi & Thierry Defrance

14:00-14:20
  • Transcription factor networks coordinate transcriptional priming and cellular expansion in early B-cell development
    Mikael Sigvardsson (Division of Molecular Hematology, Lund University, Lund, Sweden)

14:20-14:40
  • IL-7R signalling activates widespread VH and DH gene usage to drive antibody diversity in bone marrow B cells
    Anne Corcoran (Lymphocyte Signalling and Development Programme, Babraham Institute, Cambridge, UK)

14:40-15:00
  • Tracking neonatal B cell function in the adult gut
    Joan Yuan (Division for Molecular Hematology, Lund Stem Cell Center, Department of Laboratory Medicine, Faculty of Medicine, Lund University, Lund, Sweden)

15:00-15:20
  • Siglec-G controls the severity of Chronic Lymphocytic B-cell Leukemia
    Lars Nitschke (Division of Genetics, Department of Biology, University of Erlangen, Erlangen, Germany)

15:20-15:40
  • Continuous MYD88 activation is associated with expansion and then transformation of IgM differentiating plasma cells
    Christelle Vincent-Fabert (UMR CNRS 7276/INSERM U1262 CRIBL. University of Limoges, and hematology Laboratory of Dupuytren Hospital University Center (CHU) of Limoges, France)

15:40-15:47

Sponsor - Cytek Biosciences

  • Logo Cytek Biosciences How spectral flow could be the solution for your lab
    Juliette Desfrançois - Cytek Biosciences

15:47-16:00

Break


16:00-16:45

Keynote lecture

  • Memory B cells differentiation
    Dr Charlotte Viant (Laboratory of Molecular Immunology, The Rockefeller University, New York, USA)

16:45-17:15

EBCnet General assembly