Ecopa 2018

5-6 November 2018 in Paris

Bandeau JT AFC 2017

Monday 5 November

08:00-09:15

Registration

09:15-09:30

Opening of the ECOPA 2018 symposium

F. MARANO, President of FRANCOPA


09:30-10:00

Opening Keynote

Modeling Human pathogenesis using novel in vitro and in silico methods
Robert BAROUKI (INSERM - UMR-S 747)

10:00-12:00

Session 1 - System biology and physiopathology

Chair: K. WAGNER (Deutscher Tierschutzbund e.V. - German Animal Welfare Federation)

10:00-10:30

Keynote 1:
From Organ-on-a-Chip Tools Towards Patients on Chips - Enforcing a Paradigm Shift in Drug Development

U. MARX (TissUse, GmbH)


10:30-10:50

Oral presentations 1.1
Prion diseases: toward further reduction of animal experimentation
M. MOUDJOU (INRA)

10:50-11:10

Oral presentations 1.2
Drosophila: an alternative model for the modeling of human pathologies and the search for new therapies
H. TRICOIRE (Paris-Diderot University - UMR 8251 Unité BFA)

11:10-11:30

Oral presentations 1.3
Genotoxic and carcinogenic potential of 160 mycotoxins in human cells
M. AUDEBERT (INRA, UMR1331 Toxalim)

11:30-11:50

Oral presentations 1.4
Zebrafish larva: a reliable alternative of mammalian model to evaluate the impact of environmental contaminants on the mechanisms of liver disease progression
M. IMRAN (INSERM - IRSET - UMR S 1085)

12:00-13:00

Lunch & Poster presentation

13:00-14:50

Session 2 - Organoids & organ on Chip

Chair: L. BASTOS (Eurogroup for Animals)

13:00-13:30

Keynote 2:
Organoids, organs-on-chip, 3D bioprinting in a 3R context

X. GIDROL (CEA)


13:30-13:50

Oral presentations 2.1
Innovative 3D culture model of human hepatocytes with large potential applications
S. LANGOUET-PRIGENT (INSERM)

13:50-14:10

Oral presentations 2.2
HepatoPearls: New generation of liver-mimicking spheroids
N. DIANAT (CYPRIO)

14:10-14:30

Oral presentations 2.3
Development of a novel in vitro aerosol exposure system: the independent holistic air-liquid aerosol exposure system (inhales)
S. STEINER (Philip Morris International R&D)

14:30-14:50

Oral presentations 2.4
Neurospheres for Species-Specific, Medium-Throughput Analyses of Developmental Neurotoxicity (DNT) Evaluation
E. FRITSCHE (IUF - Leibniz Research Institute for Environmental Medicine)

14:50-15:15

Coffee break & Poster session

15:15-17:05

Session 3 - Omics, Biomaps, Exposome

Chair: JP. BEAUFAYS (Namur University - Faculty of Sciences) to be confirmed

15:15-15:45

Keynote 3:
Input of proteomic analyses for understanding cellular responses to nanoparticles: toward mechanistic data and evidence for cross-toxic effects

T. RABILLOUD (CEA)


15:45-16:05

Oral presentations 3.1
High throughput techniques for a predictive toxicology
R. GRALL (CEA)

16:05-16:25

Oral presentations 3.2
Role of Persistant Organics Pollutants and adipocytes in the acquisition of a metastatic potential and of chemoresistance in breast cancer
C. TOMKIEWICZ-RAULET or M. KOUAL (INSERM)

16:25-16:45

Oral presentations 3.3
Modern science for 3Rs alternative approaches and better quality control of human vaccines
S. UHLRICH (SANOFI PASTEUR)

16:45-17:05

Oral presentations 3.4
Development of SENS-IS, an in vitro assay to measure skin sensitization potency of chemicals
H. GROUX (IMMUNOSEARCH)

17:05-17:45

Posters presentation

17:45

ECOPA General Assembly for ECOPA members only