SFI 2016

28 to 30 November 2016 - Cité des Sciences et de l’Industrie, Paris, France

SFI 2016 header

Wednesday 30 November

08:00-08:30

Espaces S1/S2Welcome coffee

08:30-10:00

Plenary Session: Pierre Grabar Lectures

Amphi. Gaston Berger

Chairs: Philippe Kourilsky - Collège de France - Paris (FR) and Pierre Golstein - Centre d’Immunologie de Marseille-Luminy, Inserm, CNRS, Université Aix-Marseille (FR)

  • Federica Sallusto - Institute for Research in Biomedicine - Bellinzona (CH): Human T cell repertoires in immunity, autoimmunity and allergy
  • Mark Davis - Stanford University (US): Nature, nurture and the αβ T cell receptor repertoire
10:00-10:45

Espaces S1/S2Coffee break - Visit of exhibition - Poster session

Parallel Sessions

10:45-12:15

Activation and effector molecules in T cell immune responses   Logo Imagine

Amphi. Gaston Berger

Chairs: Anne-Sophie Korganow - Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, CNRS - Strasbourg (FR) and Armand Bensussan - Inserm, Université Paris VII-USPC - Paris (FR)

  • Geneviève de Saint Basile - Institut Imagine, Inserm, Université Paris V-USPC - Paris (FR): Lymphocyte cytotoxicity in immune homeostasis: learning from the study of primary cytotoxicity-deficiencies
  • Bernard Malissen - Centre d’Immunologie de Marseille-Luminy, Université Aix-Marseille, Inserm, CNRS - Marseille (FR): Toward an integrative biology of T cells and dendritic cells

Selected short oral presentations

  • Ulf Gehrman - Institut Curie - Paris (FR): Epigenetic control of naïve CD4+ T cell plasticity
  • Geoffrey Guittard - Centre de Recherche en Cancérologie de Marseille (FR): Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance
  • Émilie Ronin - Centre d’Immunologie et des Maladies Infectieuses, Inserm, Université Paris VI, Sorbonne Universités - Paris (FR): Role of NFkB in the biology of FoxP3+ regulatory T cells at steady state and during inflammation

10:45-12:15

Allergic, effector and suppressive responses

Salle Louis Armand Est

Chairs: Benoît Salomon - Centre d’Immunologie et de Maladies Infectieuses, Inserm, Université Paris VI-Sorbonne Universités - Paris (FR) and Jean-François Nicolas - Centre International de Recherche en Infectiologie, Inserm, Univ. Lyon1 - Pierre-Bénite (FR)

  • Sebastian Amigorena - Institut Curie, Inserm - Paris (FR): Antigen presentation and T cell activation by dendritic cells
  • Pierre Bruhns - Institut Pasteur, Inserm - Paris (FR): Mechanisms of allergic shock in humans: results from the multicentric NASA study

Selected short oral presentations

  • Séverine Bézie - Inserm - Nantes (FR): A new population of human IFNγ+IL -10+IL -34+ secreting CD8+CD45RClow Tregs efficiently inhibits anti-donor immune response
  • Bénédicte Machiels - Institute for Fundamental and Applied Research in Animal Health - Liège (B): A respiratory γherpesvirus infection protects against allergic asthma through alveolar recruitment of regulatory monocytes
  • Biliana Todorova - Institut Pasteur - Paris (FR): In vivo whole body imaging of allergic shock

10:45-12:15

Swiss Society for Allergology and Immunology (SSAI):    Logo SSAI
Session Infection and inflammation

Salle Louis Armand Ouest

Chair: Stéphanie Hugues - University of Geneva Medical School - (CH)

  • Michel Gilliet - Centre Hospitalier Universitaire Vaudois - Lausanne (CH): Recruitment and activation of plasmacytoid dendritic cells in injured skin is controlled by commensal bacteria
  • Annette Oxenius - Swiss Federal Institute of Technology - Zurich (CH): Regulation of adaptive immunity during viral infections
  • Nicola Harris - École Polytechnique Féderale de Lausanne (CH): Impact of helminth-microbiota interactions on inflammation and immunity
12:15-13:45

Espaces S1/S2Lunch - Coffee - Visit of exhibition - Poster session

13:00-13:45
SFI General Assembly

Amphi. Gaston Berger

13:45-14:45

Plenary Session: Dysregulation of the immune system  Logo Inflamex

Amphi. Gaston Berger

Chairs: Lucienne Chatenoud - Institut Necker Enfants Malades, Inserm, CNRS, Université Paris V-USPC - Paris (FR) and Pierre-André Cazenave - Institut Pasteur, Inserm - Paris (FR)

  • Bart Lambrecht - VIB Inflammation Research Center - Gent (B): New insights in the molecular mechanism of the hygiene hypothesis
  • Christophe Benoist - Harvard Medical School - Boston (US): Quantum mechanics of immunological tolerance

Parallel Sessions

14:45-16:15

Neuroinflammation   Logo CFNI

Salle Louis Armand Ouest

Chairs: Yolande Richard - Institut Cochin, Inserm, CNRS, Université Paris V-USPC - Paris (FR) and Roland Liblau - Centre de Pathophysiologie Toulouse Purpan, Inserm, CNRS, Université de Toulouse III - Toulouse (FR)

  • Burkhard Becher - University of Zurich (CH): How T cells talk to myeloid cells: the new bad guys in autoimmunity
  • Yanick Crow - Institut Imagine, Inserm, Université Paris V-USPC - Paris (FR): Human type I interferonopathies
  • Simon Fillatreau - Institut Necker Enfants Malades, Inserm, CNRS, Université Paris V-USPC - Paris (FR): Immunosuppressive activities of B cells and plasma cells

Selected short oral presentations

  • Laurie Baert - Institut pour l'Avancée des Biosciences - La Tronche (FR): CNS-derived APRIL triggers an IL-10 anti-inflammatory response from astrocytes in multiple sclerosis
  • Xuan-Hung Nguyen - Centre de Physiopathologie Toulouse Purpan - Toulouse (FR): Use of an animal model to dissect how an adjuvanted influenza vaccine triggers narcolepsy with cataplexy

14:45-16:15

Intracellular immunity

Salle Louis Armand Est

Chairs: Myriam Labalette - Inflammation Research International Center, Université de Lille - Lille (FR) and Claire Hivroz - Institut Curie, Inserm - Paris (FR)

  • Monsef Benkirane - Institut de Génétique Humaine, CNRS - Montpellier (FR): Restriction Factors are key determinants of viral susceptibility and latency
  • Olivier Schwartz - Institut Pasteur, CNRS - Paris (FR): HIV spread and antiviral humoral responses

Selected short oral presentations

  • Anne Jarry - Université de Nantes (FR): The inflammasome of tumor cells modulates the biology of Tumor Infiltrating T lymphocytes (TILs) in colorectal cancer
  • Nadia Jeremiah - Institut Curie - Paris (FR): Intrinsic anti-proliferative activity of the innate sensor STING in T lymphocytes
  • Clémence Richetta - Centre d’Immunologie et des Maladies Infectieuses, Inserm, Université Paris VI, Sorbonne Universités - Paris (FR): Autophagy does not influence HIV replication in productively infected dendritic cells

14:45-16:15

Mucosal immunity

Amphi. Gaston Berger

Chairs: Bach-Nga Pham - Hôpital Universitaire, Université Champagne Ardennes - Reims (FR) and Paul Guglielmi - Université de Montpellier, Inserm - Montpellier (FR)

  • Nadine Cerf-Bensussan - Institut Imagine, Inserm, Université Paris V-USPC - Paris (FR): Segmented filamentous bacterium: an unusual symbiont that instructs the development of the gut immune barrier
  • Béatrice Romagnolo - Institut Cochin, Inserm, CNRS, Université Paris V-USPC - Paris (FR): Intestinal inhibition of Atg7 prevents tumor initiation through a microbiome-influenced immune response and suppresses tumor growth

Selected short oral presentations

  • Ahmed Abidi - Institut de Transplantation Urologie-Néphrologie - Nantes (FR): Interleukin-22-binding protein (IL-22BP) regulates IL-22 functions during gut homeostasis
  • Jehane Fadlallah - Centre d’Immunologie et des Maladies Infectieuses, Inserm, Université Paris VI-Sorbonne Universités - Paris (FR): Perturbed host/microbial symbiosis associated to selective human IgA deficiency
  • Jordi Gouilly - Centre de Physiopathologie Toulouse Purpan - Toulouse (FR): NKp30/NCR3 and NKp44/NCR2 microenvironment-induced alternative spliced variants orchestrate NK cell effectors functions
16:15-17:15

Prizes - Conclusion

Amphi. Gaston Berger