SFI-AFC 2017

7 to 9 November 2017 - Centre des Congrès, Reims, France

SFI-AFC 2017 header

Thursday 9 November

Plenary Session and Parallel Sessions


Innate lymphoid cells

Amphithéâtre Salle Royale (level 2)

Chairs: Anne Caignard (Paris) and Armand Bensussan (Paris)

  • Christelle Retière (Nantes): NK cells and KIR receptors
  • Nicolas Dulphy (Paris): innate lymphoid cells and hematologic malignancies
  • Kamel Benlagha (Paris): Characterization of the developmental landscape of innate RORγt+ iNKT cells

Club AC Thérapeutiques

Salle 1-2 (level 2)

Chair: Hervé Watier (Tours)

Réunion de lancement


Cytométrie de masse en immunologie et hématologie

Amphithéâtre Salle Clovis (level 2)

Modérateurs : Catherine Blanc (Paris) et Pierre Grenot (Marseille)

  • Marc Dalod (Marseille): Combining flow cytometry, single cell RNA-seq and mass cytometry to rigorously dissect monuclear phagocyte subset identities and responses during mouse cytomegalovirus infection
  • Julien Lemaître (Fontenay-aux-Roses): Granulocytes and viral persistence in HIV infection and treatment: characterization of bone marrow and peripheral blood in SIV infected cynomolgus macaques
  • Olivier Molendi-Coste (Lille): Optimal computer assisted mass cytometry analysis of immune populations response to High Fat Diet in mouse adipose tissue and liver
  • Gaëlle Dzangué-Tchoupou (Paris): Immune profiling of myositis patients: towards a better classification
  • Jacques Nunès (Marseille): AML_CyTOF - Towards immuno-profiling of AML patients by mass cytometry

Microbiologie 2

Salle 3-4 (level 2)

Modérateurs : Marielle Bouix (Thiverval-Grignon) et Pierre Burguière (Montréal, Canada)

  • Marie-Christine Bertemes (Épernay) : Intérêt de la cytométrie pour la qualité des moûts en champagne
  • Pierre Burguière (Canada) : (R)Évolution en analyses microbiennes : la cytométrie en flux, une approche multiparamétrique globale

Communications orales courtes sélectionnées

  • Nicolas Lopes Ferreira (Rueil-Malmaison) : Flow cytometric approaches dedicated to the isopropanol producer Clostridium beijerinckii DSM6423
  • Axel Fayet (Pomacle) : Étude des mécanismes d’action des phénols sur Bacillus subtilis 168 par cytométrie en flux


Grande Nef (level 1)Coffee break - Visit of exhibition - Poster session

Parallel Sessions



Salle 1-2 (level 2)

Chairs: Claude Leclerc (Paris) and Brigitte Autran (Paris)

  • Armelle Phalipon (Paris): Safety and immunogenicity of a synthetic carbohydrate-based conjugate vaccine against bacillary dysentery assessed in a phase i study in healthy adult volunteers (Partial Results)
  • Camille Locht (Lille): A live attenuated pertussis vaccine and its off-target effects

Selected short oral presentations

  • Jean-Louis Palgen (Fontenay-aux-Roses): Prime and Boost Vaccination Elicit a Distinct Innate Myeloid Cell Immune Response
  • Meryem Aloulou (Toulouse): Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

Immune therapy in oncology

Amphithéâtre Salle Royale (level 2)

Chairs: Nathalie Labarrière (Nantes) and François Lemoine (Paris)Logo labex IGO

  • Éric Tartour (Paris): Cancer vaccine at the era of checkpoint inhibitors
  • François Ghiringhelli (Dijon): Rational of combination of checkpoint inhibitors immunogenic cell death inducer

Selected short oral presentations

  • Anne Montfort (Toulouse): TNF blockade overcomes resistance to anti-PD-1 in experimental melanoma
  • Vanessa Gauttier (Nantes): Dual targeting of adaptive and innate immune checkpoints induces strong tumor microenvironment modification and potent memory anti-tumor responses
  • Grégory Fouquet (Salouël): SLAMF3: a new target of immunotherapy in HepatoCellular Carcinoma?


Amphithéâtre Salle Clovis (level 2)

Modérateurs : Francine Garnache-Ottou (Besançon) et Alain Delmer (Reims)

  • Remi Letestu (Paris) : Utiliser la maladie résiduelle par cytométrie en flux dans le suivi de la leucémie lymphoïde chronique… Pourquoi, quand, comment, et plein d’autres questions encore !
  • Magali Le Garff Tavernier (Paris) : LLC : phénotypage diagnostic, quoi de neuf ?
  • Elsa Maitre (Caen) : Place de la CMF pour le diagnostic des hémopathies cutanées

Communications orales courtes sélectionnées

  • Myrto Costopoulos (Paris) : Comparaison de la cytométrie en flux et de la biologie moléculaire pour la mise en évidence d’une dissémination lymphomateuse méningée
  • Michaël Pérès (Toulouse) Clinical and biological characteristics of B cell chronic lymphoproliferative disorder with more than one abberant B cell clone detected by flow cytometry
  • Myrto Costopoulos (Paris) : Interférences analytiques du Transfix® : une évaluation à ne pas négliger ! Application à la recherche de localisation méningée de lymphome T

Biologie végétale

Salle 3-4 (level 2)

Modérateurs : Lisa Sanchez (Reims) et Mickaël Bourge (Paris)

Communications orales courtes sélectionnées

  • Marie-Florence Ngo Ngwe (Cameroon) : Nuclear DNA content analysis and the ploidy level of Prunus africana from Cameroon
  • Perla Farhat (Orsay) : Genome size variation and exceptional high frequency of polyploidy in Juniperus genus assessed by flow cytometry
  • Sonja Siljak-Yakovlev (Paris) : Complémentarité de la cytogénétique et de la cytométrie en flux dans l'étude des populations chez les plantes
  • Mickaël Bourge (Paris) : Isolation des organites par cytométrie : état des lieux


Symposium BMS

Salle 1-2 (level 2)

Immunothérapies : de la recherche à la clinique.Logo BMS
Regards croisés en transplantation, rhumatologie et oncologie

Modérateurs : Daniel Olive (Marseille) et Sylvia Cohen-Kaminsky (Le Plessis-Robinson)

  • Daniel Olive (Marseille) et Sylvia Cohen-Kaminsky (Le Plessis-Robinson) : L’Immunothérapie : du fondamental à la pratique
  • François Ghiringhelli (Dijon) : Le point de vue de l’oncologue
  • Thierry Martin (Strasbourg) : Le point de vue de l’interniste
  • Olivier Thaunat (Lyon) : Le point de vue du transplanteur - Des souris et des hommes : dissection translationnelle de la résistance des greffons au rejet humoral
  • Conclusion / take-home messages


Parallel Sessions


Innate immunity/Dendritic cells

Amphithéâtre Salle Royale (level 2)

Chairs: Marc Dalod (Marseille) and Vassili Soumelis (Paris)

  • Sonja Buschow (The Netherlands): Human dendritic cell subsets and hepatitis B virus infection
  • Charlotte Scott (Belgium): The role of the Zeb family of transcription factors in myeloid cell biology

Selected short oral presentations

  • Jean-Francois Fonteneau (Nantes): Partial antiviral response by mesothelioma cells sensitive to the oncolytic activity of measles virus defines two types of interferon stimulated genes
  • Margaux Hubert (Lyon): BDCA3hi dendritic cells infiltrate human primary breast tumors and correlate with a good prognosis


Salle 1-2 (level 2)

Chairs: Lucienne Chatenoud (Paris) and Abdel Saoudi (Toulouse)

  • Ludger Klein (Germany): Shaping of the CD4 T cell repertoire by an auto-antigen of the central nervous system
  • Tim Sparwasser (Germany): Metabolic programs controlling immune cell function

Selected short oral presentations

  • Mehdi Benamar (Toulouse): Modulation of regulatory T cell stability and functions through the T cell receptor signaling molecules Themis1 and Vav1
  • Nora Deluce (Tours): Modulation of human dendritic cell functions by bispecific antibody targeting pathogens recognition receptors

Doctorant session

Salle 5 (level 2)

Chairs: Delphine Sauce (Paris) and Moncef Guenounou (Reims)

  • Noëlla Lopes (Marseille): Administration of RANKL boosts thymic regeneration upon bone marrow transplantation
  • Jean-Charles Cancel (Marseille): Do XCR1+ dendritic cells have a role in immunotherapies against cancer ?
  • Ève Blanquart (Toulouse): Androgen-dependent regulation of group 2 innate lymphoid cells: a new pathway to understand sex-differences in allergic asthma
  • Rami Bechara (Paris): Nickel sulfate promotes IL-17A producing CD4+ T-cells by an IL-23 dependent mechanism regulated by TLR4 and Jak-STAT pathways.
  • Justine Devulder (Lille): Impaired activation of Natural Killer cells from severe asthmatics by pathogen-like molecules

Inflammatory diseases

Salle 3-4 (level 2)

Chairs: Maria Leite-de-Moraes (Paris) and Thierry Martin (Strasbourg)Logo Inflamex

  • Renato Monteiro (Paris): Antigen receptors as molecular switches regulating inflammation
  • Harry Sokol (Paris): Microbiota, genes and Immunity in inflammatory bowel disease: from cells to human

Selected short oral presentations

  • Lyssia Belarif (Nantes): Interleukin-7 receptor pathway controls human T cell homing to the gut and predicts response to anti-TNFα therapy in patients with inflammatory bowel disease
  • Alexandre Pierre (Reims): Impact of aging on inflammatory and immune responses during elastin peptide-induced murine emphysema
  • Alexia Loste (Paris): IgE antibodies and mast cells involvement in aneurysm progression

Computational Cytometry Club (3C)

Amphithéâtre Salle Clovis (level 2)

Chairs: Antonio Cosma (Fontenay-aux-Roses) and Samuel Granjeaud (Marseille)

  • Mark Robinson (Switzerland): Differential analyses of high-dimensional cytometry data
  • Yvan Saeys (Belgium): Unraveling cell developmental dynamics using computational flow cytometry
  • Antonio Cosma (Fontenay-aux-Roses), Hervé Luche (Marseille) and Samuel Granjeaud (Marseille):
    ‘3C’: Objectives and open forum discussion

Selected short oral presentation

  • Quentin Barbier (Marseille) : Recherche automatisée de phénotypes par analyse combinatoire de marqueurs sur des données de cytométrie en flux multiparamétrique sous R et R-Shiny


Oral presentation and Poster Prize Ceremony

Amphithéâtre Salle Royale (level 2)

Plenary Session


Immune metabolism

Amphithéâtre Salle Royale (level 2)

Chairs: Naomi Taylor (Montpellier) and Benoît Salomon (Paris)

  • David Finlay (Ireland): Srebp-controlled glucose metabolism is essential for Natural Killer cell functional responses
  • Erika Pearce (Germany): Mitochondrial priming by CD28
  • Christoph Hess (Switzerland): Integrating glycolysis and respiration to support rapid recall responses of memory CD8+ T cells


Meeting closing

Amphithéâtre Salle Royale (level 2)