SFI-AFC 2022

Rhodes - Level 2 Welcome coffee

Auditorium Athéna - Level 2Debate ‘Women in Science’

Chairs: Abdelilah Wakkach (Nice), Florence Apparailly (Montpellier) &
Fatima-Ezzahra L’Faqihi-Olive (Toulouse)

• Yasmine Belkaid (Bethesda, USA): Title up coming
• Anne Hosmalin (Paris): Women in Immunology: a career perspective

Room Rhodes 9 - Level 2

SFI / Spanish Society for Immunology

Contribution of french and spanish immunology to the fight againts Covid

Chairs: Marcos López Hoyos (Santander, Spain) & Renato Monteiro (Paris)

• Olivier Schwartz (Paris): Omicron sub-variants and sub-sub-variants: viral fitness and sensitivity to the humoral response
• Estela Paz-Artal (Madrid, Spain): SARS-CoV-2 Infection and Vaccination : Real World Immunology Lessons
• Jorge Carrillo (Barcelona, Spain): Structurally guided stabilization of Spike glycoproteins for the development of novel SARS-CoV-2 vaccines

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Room Risso 6 - Level 2

AFC / SFM - Microbiology

Chairs: Marielle Bouix (Paris) & Claire Saulou-Bérion (Palaiseau)

• Lysiane Omhover (Strasbourg): Freeze-dried bacteria: between viability and stress states
• Mickael Bourge (Paris): Development of intracellular pH measurements to characterize the physiology of bacteroids in the legume-rhizobium symbiosis by combining cytometry and imaging

Selected short oral presentations

• Laetitia Velly (Paris): Optimal combination of early biomarkers for infection and sepsis diagnosis in the emergency department: The BIPS study
• Clément Trunet (Quimper): Rapid flow cytometry methodology for airborne fungal conidia enumeration
• Sophie Servain-Viel (Orsay): Flow Cytometry Method for Safe Detection of Bacterial Viability

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Auditorium Athéna - Level 2

AFC / CytHem - New cytometers, new panels, new regulation

Chairs: Michel Ticchioni (Nice) & Magali Le Garff-Tavernier (Paris)

• Bernard Chatelain (Yvoir, Belgium): Reflections on the implementation and use of the FACS Lyric flow cytometer at the CHU UCL Namur
• Christophe Roumier (Lille): Du Navios au DX Flex (Beckman Coulter) : impact du changement de technologie (10 PMT vs 13 APD, Digitalisation 20 Bits vs 24 Bits) en pratique au laboratoire
• Françoise Durrieu (Bordeaux): New cytometer and new panels in an acrredited routine lab: experience of the Dxflex implementation

Selected short oral presentations

• Nicolas Voirin-Mathieu (Limoges): Performance analysis of new 10-color cytometer: XF-1600® Sysmex
• Magali Le Garff-Tavernier (Paris): Phenotypic profile of Waldenström Macroglobulinemia B cells: from determination of a diagnostic score to development of a 12-color flow cytometry panel

Rhodes - Level 2 Coffee break - Visit of exhibition - Posters

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Poster Prize audition

Auditorium Athéna - Level 2

Data analysis

Chairs: Aïda Meghraoui-Kheddar (Biot) & Samuel Granjeaud (Marseille)

•  Keren Leeat (Tel-Aviv, Israel): Unraveling the tumor immune microenvironment in melanoma by multiplexed imaging

Selected short oral presentations

• Manon Scholaert (Toulouse): MANTIS: an integrated digital process for 3-D deconstruction of human skin immune landscape
• Yvonne Scuiller (Brest): In-depth analysis of salivary gland biopsies: Development of new tools using Hyperion mass cytometry to accurately determine Sjögren’s severity status
• Quentin Blampey (Villejuif): Scyan: an interpretable generative model for multi-task cytometry analysis
• Julien Nourikyan (Lyon): Robust Identification of biomarkers through a clustering approach guided by patient outcomes: application in B-cell ALL, melanoma and rheumatoid arthritis
• Yann Abraham (Beerse, Belgium): Data-driven identification of cell states in cytometry experiments

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Room Risso 6 - Level 2

Transplant immunology

Chairs: Alice Koenig (Lyon) & Julien Zuber (Bordeaux)

• Hannah Kaminski (Bordeaux): Amis : L’immunité innée dans les infections et les cancers des receveurs d’allogreffe
• Olivier Thaunat (Lyon): Ennemis : L’immunité innée dans l’alloreconnaissance et les lésions de rejet d’allogreffe

Selected short oral presentations

• Nassim Salem (Marseille): Combined CAR-NK and CARgd T cells promote the killing of leukemic blasts
• Lorenzo Canti (Liège, Belgium): Integrative Approach in the Context of BNT162b2 mRNA Covid-19 Vaccine in Allo-HCT Patients: System Vaccinology

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Room Rhodes 9 - Level 2

Environmental control of myeloid cells

Chairs: Fabienne Anjuère (Valbonne) & Florent Ginhoux (Villejuif)

• Thomas Simon (Valbonne): Treatment of autoimmune diseases by neuromodulation
• Christopher Mueller (Strasbourg): Immune-microenvironment: cell specification in lymphoid organ niches

Selected short oral presentations

• Bastien Dolfi (Nice): Decipher the diversity and function of adrenal gland macrophages
• Maya Saleh (Bordeaux): Single cell and spatial transcriptomics unravel TREM1+CD163+ myeloid cells as potent immunosuppressive cells associated with poor survival in human liver cancer

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Room Gallieni 5 - Level 2

AFC / CytHem: T- and NK- cell lymphoma

Chairs: Mikael Roussel (Rennes) & Alessandra Rosenthal (Nice)

• Mikael Roussel (Rennes): Diagnostic de LGL : vers une approche intégrée
• Laurence De Leval (Lausanne, Switzerland): Classification of T-cell lymphomas
• Hélène Moins (Paris): Diagnostic et suivi par cytométrie du S. de Sezary - Groupe Cythem Sezary

Selected short oral presentation

• Rémi Letestu (Bobigny): Étude de l’expression de TRBC1 par CMF comme marqueur de substitution de la clonalité lymphoïde T : une évaluation monocentrique de l’anticorps JOVI-1

Rhodes - Level 2 Lunch

Coffee - Visit of exhibition - Posters

Room Rhodes 9 - Level 2

Immuno-Oncologie : La révolution continue

Modérateurs : François Lemoine (Paris) & Lisa Derosa (Paris)

• Marie-Caroline Dieu-Nosjean (Paris) : Tumor-associated Tertiary lymphoid structures, a major ‘headquarters’ for the development of efficient immune responses against cancers
• Lisa Derosa (Paris) : Impact du microbiote sur les biothérapies et les réponses anti-tumorales
•  François-Xavier Danlos (Paris) : Mécanismes de résistance aux immunothérapies par anticorps monoclonaux anti-PD1
• Eric Tartour (Paris) : Therapeutic cancer vaccine
• Makoto Miyara (Paris) : CAR T cells : avancées et enjeux en Oncologie
• Michael Loschi (Nice) : CAR T cells et hémopathies malignes
• Table ronde

Auditorium Athéna - Level 2

High content cytometry

Chairs: Anne-Sophie Chrétien (Marseille) & Catherine Blanc (Paris)

• Henrik Mei (Berlin, Germany): Probing the Immune System by Mass(ive) Cytometry
• Emeric Limagne (Dijon): Spectral flow cytometry: a tool for characterizing the tumor microenvironment in preclinical models

Selected short oral presentations

• Olivier Molendi-Coste (Lille): A CyTOF atlas of human cardiac immunity
• Tom Dott (Paris): High-dimensional spectral cytometry panels for whole blood immune phenotyping in the Milieu Interieur 10-year longitudinal study

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Room Gallieni 5 - Level 2

Hematopoiesis

Chairs: Tsvee Lapidot (Rehovot, Israel) & Noushin Mossadegh-Keller (Marseille)

• Tsvee Lapidot (Tel-Aviv, Israel): Circadian regulation of hematopoietic stem cells and host immunity by light and darkness cues
• Elisa Gomez-Perdiguero (Paris): Progenitor waves interplay during development to build the immune system
• Karl Balabanian (Paris): CXCR4 signaling, a gatekeeper orchestrating the bone marrow ecosystem

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Room Risso 6 - Level 2

Microbiota

Chairs: Sophie Brouard (Nantes) & David Moulin (Nancy)

• Valérie Gaboriau-Routhiau (Paris): The Segmented Filamentous Bacterium: a paradoxical bacterium
• Mario Zaiss (Erlangen, Germany): Gut microbiota-derived metabolites in the regulation of inflammatory diseases

Selected short oral presentations

• Léo Bertrand (Paris): Microbiota in type 1 diabetes induces circulatory and intestinal MAIT cell dysfunction and increases liver and pancreas pro-inflammatory immune landscapes
• Patrícia Brito Rodrigues (Campinas, Brazil): SARS-CoV-2 gamma variant induces microbiota changes and impairs intestinal epithelium tight junctions in mice
• Rémy Villette (Paris): Secretory IgA and gut microbiota at birth influence allergic clinical outcome

Rhodes - Level 2 Poster Session 2 - even-numbered posters

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Rhodes - Level 2 Coffee break - Visit of exhibition

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Poster Prize audition

Auditorium Athéna - Level 2Industry Symposium

Chairs: Muriel Andrieu (Paris) & Lennart Mars (Lille)

• Cytek Biosciences
  Application of high-dimensional spectral cytometry to the evaluation of drug responses in AML patient samples
  Laure Delestré (Institut Gustave Roussy, Villejuif)

Auditorium Athéna - Level 2Young scientists

Chairs: Noushin Mossadegh-Keller (Marseille), Mathieu Chevalier (Paris), Laetitia Gautreau-Rolland (Nantes), Fatima-Ezzahra L’Faqihi-Olive (Toulouse),
Catherine Blanc (Paris) & Anne-Sophie Chrétien (Marseille)

• Noushin Mossadegh-Keller, Vice-President of the SFI: Introduction

Selected short oral presentations

• Julie Noguerol (Toulouse): H3K9me3-dependent epigenetic pathways control CD4 T cell responses to Treg-mediated suppression
• François Santinon (Montreal, Canada): Identification of p-eIF4E as a new regulator of regulatory T-cell activity
• Aurora Pignata (Toulouse): Investigating the role of Tissue-resident memory T cells in chronic CNS autoimmune disease
• Morgane Gossez-Coulaud (Lyon): Regulatory plasma cells are induced after bacterial and SARS-CoV-2 sepsis and inhibit T cell function through increased PD-L1 expression

+ Best PhD article Award

Room Risso 6 - Level 2AFC General Assembly

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Auditorium Athéna - Level 2SFI General Assembly

Meeting Dinner