SFI 2019

12 to 14 November 2019 - Nantes events Center, Nantes, France

SFI 2019 header

Tuesday 12 November


Mezzanine (Level 2)Meeting registration


Auditorium 450 (Level 2)Welcome introduction

Renato Monteiro, President of the SFI


Logo nextAttracting high potential scientific talents to Nantes
Jean-Baptiste Avrillier, Operational Director of The NExT initiative

Plenary Session


Auditorium 450 (Level 2)Immunoregulation

Chairs: Ignacio Anegon (Nantes, France) and Aurélie Moreau (Nantes, France) Logo labex IGO

  • Simon Fillatreau (Paris, France): Antibody-independent functions of B cells and plasma cells through cytokine production
  • Anne Müller (Zurich, Switzerland): Host and pathogen determinants of chronic bacterial infection
  • Derk Amsen (Amsterdam, The Netherlands): Probing regulatory T cell identity by shotgun mass spectrometry


Mezzanine & Espace R2 (Level 2)Coffee break - Visit of exhibition & Posters

Parallel Sessions


Auditorium 450 (Level 2)Innate control of inflammation

Chairs: Sophie Laffont (Toulouse, France) and Julie Tabiasco (Toulouse, France)

Selected short oral presentations

  • Alice Lepelley (Paris, France): Loss-of-function of COPA highlights the importance of the STING ER-Golgi axis in type I interferon signalling
  • Edouard Leveque (Toulouse, France): Eicosanoids: a new step in deciphering mast cells/CD4+ T cells Crosstalk
  • Nikaïa Smith (Paris, France): Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement - A new target for lupus treatment


Salle I (Level 2)Session DGFI (Deutsche Gesellschaft für Immunologie)

Chairs: Michael Lohoff (Marburg, Germany) and Luciana Berod (Hanovre, Germany)

  • Dirk Brenner (Luxembourg, Luxembourg): cROSsing the line: Controlling T cell metabolism
  • Birgit Sawitzki (Berlin, Germany): Checkpoint receptors in CD4+ helper T cell differentiation
  • Dietmar Zehn (Freising/Munich, Germany): InTOXication causes T-cell exhaustion in chronic infection


Salle 200 (Level 2)Single-cell analysis and handling Big Data

Chairs: Vassili Soumelis (Paris, France) and Mickaël Ploquin (Pleasanton, CA, USA) Logo 10xgenomics

  • Pierre Milpied (Marseille, France): Single-cell analyses of differentiation and plasticity in normal and malignant B cells
  • Andrei Zinovyev (Paris, France): Advances and challenges of the single-cell data analysis

Selected short oral presentations

  • Etienne Becht (Seattle, WA, USA): Infinity Flow: Comprehensive Single-Cell Protein Profiling via Massively Parallel Flow Cytometry and Machine Learning
  • Thomas Laurent (Nantes, France): Longitudinal analysis of immune cells in kidney transplantation rejection by single-cell RNA-seq
  • Céline Sérazin (Nantes, France): Single cell transcriptomic analysis for a better understanding of human CD8+ regulatory T cells


Salle G-H (Level 2)Transplantation

Chairs: Gilles Blancho (Nantes, France) and Sophie Brouard (Nantes, France)

  • Olivier Thaunat (Lyon, France): Immunopathology of chronic rejection: is it all antibody-mediated?
  • Benjamin Stewart (Cambridge, UK): Tissue immunity - implications for transplantation

Selected short oral presentations

  • Séverine Bézie (Nantes, France): Human CD8+ Treg expressing a MHC-specific chimeric antigen receptor display-enhanced suppression of human skin rejection and GVHD in NSG mice
  • Florian Dubois (Nantes, France): Identification of a common transcriptional pattern for regulatory B cells through meta-analysis
  • Gabriel Marsères (Bordeaux, France): γδ T cell-based immunotherapy against CMV infection after transplantation: a preclinical study


Espace R0 (Level 0)Lunch

Mezzanine & Espace R2 (Level 2)Coffee - Visit of exhibition & Posters

Parallel Sessions


Salle 200 (Level 2)ASSIM General Assembly


Auditorium 450 (Level 2)Industry Symposium

Chairs: Véronique Witko-Sarsat (Paris, France) and Abdelhadi Saoudi (Toulouse, France)

  • 14:15-14:19  Logo BerkeleyBerkeley Lights
    Berkeley Lights Inc’s Optofluidic Platforms: Linking Genotype to Phenotype at the
    Single Cell Level And More
    Jean-Baptiste Pénigault
  • 14:19-14:27  Logo Cell-Signaling-TechnologyCell Signaling Technology
    Achieving Reproducible Science: Don’t Let Antibodies be a Variable in Your Experiment
    Federica Cioffi
  • 14:27-14:35  Logo StemcelStemcell Technologies
    Tools & Reagents For Your Immunology Research
    Graeme Milton
  • 14:35-14:43  Logo Bd BiosciencesBD Biosciences
    How to resolve heterogeneity: the BD Multi-Omics Solution
    Rodriguez Werner
  • 14:43-14:51  Logo FluidigmFluidigm
    High-Dimensional Immune Monitoring, Simplified
    Easily quantify 37 immune subsets from PBMC and whole blood using mass cytometry
    Emilie Gregori
  • 14:51-14:59  Logo Beckman CoulterBeckman Coulter
    New Tools for advanced cellular analysis by flow cytometry
    Fabrice Malergue
  • 14:59-15:07  Logo 10xgenomics10x Genomics
    Immunology at single cell resolution: Antigen Specificity, Immune Repertoire, and Cellular Phenotype Using Single Cell Transcriptomics
    Christophe Fleury
  • 15:07-15:15  Logo Bio-techneBio-techne
    New Rapid Immunoassay Solutions: Quantikine quality in a fraction of the time
    Warren Higgs

Plenary Session


Auditorium 450 (Level 2)Cancer Immunology

Chairs: Régis Josien (Nantes, France) and Nicolas Poirier (Nantes, France) Logo OSE

  • Miriam Merad (New-York, USA): Myeloid Determinants of Tumor Immunity
  • Alexandre Boissonnas (Paris, France): Treg/monocyte crosstalk following conventional cancer therapies


Mezzanine & Espace R2 (Level 2)Coffee break - Visit of exhibition & Posters

Parallel Sessions


Auditorium 450 (Level 2)Cancer Immunotherapy

Chairs: Nathalie Labarrière (Nantes, France) and Catherine Rabu (Nantes, France)

  • Éric Tartour (Paris, France): Resident memory T cells and cancer immunotherapy
  • Jürgen Kuball (Utrecht, The Netherlands): γδ TCR engineered T cells

Selected short oral presentations

  • Emilie Dupré (Nantes, France): A novel strategy to identify melanoma-antigen from long non coding RNA
  • Irini Evnouchidou (Paris, France): IRAP-dependent TCR endosomal signalling is essential for T cell response
  • Ludovic Martinet (Toulouse, France): Eomes-dependent CD226 loss alters TCR responsiveness and restrains CD8+ T lymphocyte anti-tumor functions


Salle G-H (Level 2)Germinal Center Club

Chairs: Nicolas Fazilleau (Toulouse, France), Marion Espeli (Clamart, France) and Patricia Amé-Thomas (Rennes, France)

  • Céline Delaloy (Rennes, France): IL-2, BACH2 and B cell fate programming near the germinal center
  • Julia Jellusova (Freiburg, Germany): The role of the multifunctional autophagy adaptor protein p62/SQSTM1 in B cell activation and metabolism

Selected short oral presentations

  • Amélie Bonaud (Paris, France): Analysis of SNARE-mediated regulation of plasma cell biology
  • Manuel D. Diaz-Munoz (Toulouse, France): The RNA-binding protein HuR is required for germinal center responses and high-affinity antibody production
  • Virginie Tardif (Philadelphia, PA, USA): A Novel Follicular Regulatory Innate Lymphoid Cell (ILCFR) Population present in human tonsils disrupts germinal centers and expands in chronic viral infection


Salle 200 (Level 2)NeuroImmunology Club

Chairs: Lennart Mars (Lille, France) and Sylvia Cohen-Kaminsky (Le Plessis-Robinson, France)

  • Doron Merkler (Geneva, Switzerland): Cytotoxic T cells as drivers of immunopathology in the central nervous system
  • Roland Liblau (Toulouse, France): Learning from animal models to understand the pathophysiology of Narcolepsy and Susac syndrome
  • Alexander Flügel (Goettingen, Germany): β-synuclein-reactive T cells cause autoimmune CNS grey matter degeneration


Salle I (Level 2)Mast Cell/Basophil Club

Chairs: Adrian Piliponsky (Seattle, USA) and Nicolas Gaudenzio (Toulouse, France)

  • Adrian Piliponsky (Seattle, USA): Unraveling the role of mast cells and basophils in innate immunity and sepsis

Selected short oral presentations

  • Ulrich Blank (Paris, France): Mast cell chymase limits neutrophil activation and recruitment protecting against ischemic reperfusion injury
  • Mei Li (Illkirch, France): IL-3 plays a crucial role in basophil extravasation to mouse skin with allergic contact dermatitis
  • Laurent Reber (Toulouse, France): Characterization of a novel mouse model humanized for IgE and its high-affinity receptor FcεRI
  • Marie Tauber (Toulouse, France): A new mouse model of mast cell-deficiency based on the specific depletion of Mrgrpb2-expressing cells


Mezzanine & Espace R2 (Level 2)Poster Session 1

& Welcome cocktail

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